Data di Pubblicazione:
2018
Citazione:
Aziridination of alkenes promoted by iron or ruthenium complexes / C. Damiano, D. Intrieri, E. Gallo. - In: INORGANICA CHIMICA ACTA. - ISSN 0020-1693. - 470(2018 Jan), pp. 51-67. [10.1016/j.ica.2017.06.032]
Abstract:
Molecules containing an aziridine functional group are a versatile class of organic synthons due to the presence of a strained three member, which can be easily involved in ring-opening reactions and the aziridine functionality often show interesting pharmaceutical and/or biological behaviours. For these reasons, the scientific community is constantly interested in developing efficient procedures to introduce an aziridine moiety into organic skeletons and the one-pot reaction of an alkene double bond with a nitrene [NR] source is a powerful synthetic strategy.Herein we describe the catalytic activity of iron or ruthenium complexes in promoting the reaction stated above by stressing the potential and limits of each synthetic protocol.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Aziridines; Nitrene reagents; Alkenes; Homogenous catalysis; Iron; Ruthenium
Elenco autori:
C. Damiano, D. Intrieri, E. Gallo
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