1,2-Dihydro-1,2-dihydroxynaphthalene dehydrogenase containing recombinant strains: Preparation, isolation and characterisation of 1,2-dihydroxynaphthalenes and 1,2-naphthoquinones
Articolo
Data di Pubblicazione:
1999
Citazione:
1,2-Dihydro-1,2-dihydroxynaphthalene dehydrogenase containing recombinant strains: Preparation, isolation and characterisation of 1,2-dihydroxynaphthalenes and 1,2-naphthoquinones / C. Cavallotti, F. Orsini, G. Sello, P. Di Gennaro, E. Galli, G. Bestetti. - In: TETRAHEDRON. - ISSN 0040-4020. - 55:14(1999), pp. 4467-4480.
Abstract:
1,2-Dihydroxynaphthalenes are produced by dehydrogenation of the corresponding 1,2-dihydro-1,2-dihydroxynaphthalenes using an Escherichia coli recombinant strain containing the dihydrodiol naphthalene dehydrogenase gene cloned from Pseudomonas fluorescens N3. Conversions are led in carefully controlled conditions to minimise product polymerisation. A multistep procedure using a weakly basic resin permits isolation of good product amounts, solving the toxicity problem. Products are isolated and characterised as t-butyldimethylsilyl derivatives that are stable compounds. The transformation of the 1,2-dihydroxynaphthalenes into the corresponding 1,2-naphthoquinones is also reported.
Tipologia IRIS:
01 - Articolo su periodico
Elenco autori:
C. Cavallotti, F. Orsini, G. Sello, P. Di Gennaro, E. Galli, G. Bestetti
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