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Use of Nutritional Strategies, Bioactive Compounds, and Dietary Supplements in Young Athletes: From Evidence to Potential Risks—A Narrative Review

Articolo
Data di Pubblicazione:
2025
Citazione:
Use of Nutritional Strategies, Bioactive Compounds, and Dietary Supplements in Young Athletes: From Evidence to Potential Risks—A Narrative Review / D. De Zan, F. Eletti, G. Fiore, E. Di Girolamo, G.G.M. Bozzini, V. Perico, M. Tosi, L. Norsa, G. Zuccotti, E. Verduci. - In: NUTRIENTS. - ISSN 2072-6643. - 17:13(2025 Jun), pp. 2194.1-2194.23. [10.3390/nu17132194]
Abstract:
Young athletes face unique nutritional challenges due to their simultaneous engagement in intensive physical training and ongoing growth and development. Standard adult-based dietary recommendations often fail to meet the specific needs of this population. While the role of macronutrients and micronutrients is well recognized, increasing attention is being paid to bioactive compounds—non-essential food-derived elements with potential health benefits. This review aims to summarize current evidence regarding the efficacy, safety, and potential benefits of bioactive compounds in the nutritional management of young athletes. Methods: A narrative review of the literature published over the last 30 years was conducted across PubMed/Medline, Embase, and Scopus databases to identify relevant studies published in English. The inclusion criteria covered original research articles, clinical trials, cohort and case-control studies, and meta-analyses focusing on individuals aged 8–20 years. Studies addressing supplementation strategies, physiological effects, and safety concerns of bioactive compounds in young athletes were selected. Preclinical data and adult-based studies were also included to contextualize molecular mechanisms and support clinical findings. Results: The review highlights that bioactive compounds such as omega-3 fatty acids, curcumin, caffeine, and creatine as well as antioxidant vitamins may play a beneficial role in improving recovery, immune function, and performance in young athletes. Of these 21 studies, 8 focused on recovery and muscle soreness, 6 addressed immune function or antioxidant/anti-inflammatory effects, and 7 investigated direct performance enhancement. However, most of the available evidence derives from adult populations, and pediatric-specific data remain limited. Concerns remain about the misuse of supplements, lack of professional guidance, and potential contamination with banned substances. Conclusions: While some bioactive compounds show promising potential to support the health and performance of young athletes, current evidence is insufficient to support routine use in this population. More pediatric-specific research is necessary to establish safety, efficacy, and appropriate supplementation protocols tailored to young athletes’ unique physiological needs.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
nutrition; young athletes; bioactive compounds; macronutrients; micronutrients; antioxidant vitamins; ergogenic supplements; nitrates; nutraceuticals
Elenco autori:
D. De Zan, F. Eletti, G. Fiore, E. Di Girolamo, G.G.M. Bozzini, V. Perico, M. Tosi, L. Norsa, G. Zuccotti, E. Verduci
Autori di Ateneo:
ELETTI FRANCESCA ( autore )
FIORE GIULIA ( autore )
PERICO VERONICA ( autore )
TOSI MARTINA ( autore )
VERDUCI ELVIRA ( autore )
ZUCCOTTI GIAN VINCENZO ( autore )
Link alla scheda completa:
https://air.unimi.it/handle/2434/1174018
Link al Full Text:
https://air.unimi.it/retrieve/handle/2434/1174018/3104861/nutrients-17-02194.pdf
Progetto:
ON Foods - Research and innovation network on food and nutrition Sustainability, Safety and Security – Working ON Foods
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Settori (3)


Settore MEDF-01/A - Metodi e didattiche delle attività motorie

Settore MEDS-08/C - Scienza dell'alimentazione e delle tecniche dietetiche applicate

Settore MEDS-20/A - Pediatria generale e specialistica
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