Temporal asymmetries of short-term heart period variability are linked to autonomic regulation
Articolo
Data di Pubblicazione:
2008
Citazione:
Temporal asymmetries of short-term heart period variability are linked to autonomic regulation / A. Porta, K.R. Casali, A.G. Casali, T. Gnecchi-Ruscone, E. Tobaldini, N. Montano, S. Lange, D. Geue, D. Cysarz, P. van Leeuwen. - In: AMERICAN JOURNAL OF PHYSIOLOGY. REGULATORY, INTEGRATIVE AND COMPARATIVE PHYSIOLOGY. - ISSN 0363-6119. - 295:2(2008), pp. R550-R557. [10.1152/ajpregu.00129.2008]
Abstract:
We exploit time reversibility analysis, checking the invariance of statistical features of a series after time reversal, to detect temporal asymmetries of short-term heart period variability series. Reversibility indexes were extracted from 22 healthy fetuses between 16th to 40th wk of gestation and from 17 healthy humans (aged 21 to 54, median = 28) during graded head-up tilt with table inclination angles randomly selected inside the set {15, 30, 45, 60, 75, 90}. Irreversibility analysis showed that nonlinear dynamics observed in short-term heart period variability are mostly due to asymmetric patterns characterized by bradycardic runs shorter than tachycardic ones. These temporal asymmetries were 1) more likely over short temporal scales than over longer, dominant ones; 2) more frequent during the late period of pregnancy (from 25th to 40th week of gestation); 3) significantly present in healthy humans at rest in supine position; 4) more numerous during 75 and 90° head-up tilt. Results suggest that asymmetric patterns observable in short-term heart period variability might be the result of a fully developed autonomic regulation and that an important shift of the sympathovagal balance toward sympathetic predominance (and vagal withdrawal) can increase their presence.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Autonomic nervous system; Fetal maturation; Head-up tilt; Heart rate variability; Nonlinear dynamics
Elenco autori:
A. Porta, K.R. Casali, A.G. Casali, T. Gnecchi Ruscone, E. Tobaldini, N. Montano, S. Lange, D. Geue, D. Cysarz, P. van Leeuwen
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