Determination of the UV Inactivation Constant Under 280 Nm UV LED Irradiation for SARS-CoV-2
Articolo
Data di Pubblicazione:
2022
Citazione:
Determination of the UV Inactivation Constant Under 280 Nm UV LED Irradiation for SARS-CoV-2 / S. Biffi, L. Signorini, L. Cattaneo, L. Della Corna, A. Guercilena, S. D'Alessandro, P. Ferrante, S. Delbue. - In: PHOTOCHEMISTRY AND PHOTOBIOLOGY. - ISSN 1751-1097. - (2022). [Epub ahead of print] [10.1111/php.13653]
Abstract:
The ongoing emergency provoked by the SARS-CoV-2 pandemic demands the development of technologies to mitigate the spread of infection, and UV irradiation is a technique that can efficiently address this issue. However, proper use of UV equipment for disinfection requires an understanding of how the effects on SARS-CoV-2 are dependent on certain parameters. In this work, we determined the UV-C inactivation constant k for SARS-CoV-2 using an LED source at lambda = 280 nm. Specifically, a Log3 reduction was measured after irradiation for 24 min with a delivered UV-C dose of 23 J m(-2). By multitarget model fitting, n = 2 and k = 0.32 +/- 0.02 m(2) J(-1) were obtained. A lag time for the inactivation effect was also observed, which was attributed to the low irradiation levels used to perform the study. The combination of k and delay time allows for reliable estimation of disinfection times in small, closed environments.
Tipologia IRIS:
01 - Articolo su periodico
Elenco autori:
S. Biffi, L. Signorini, L. Cattaneo, L. Della Corna, A. Guercilena, S. D'Alessandro, P. Ferrante, S. Delbue
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