Causal analysis is needed to evaluate cardiorespiratory interaction alterations in postural orthostatic tachycardia syndrome patients
Articolo
Data di Pubblicazione:
2021
Citazione:
Causal analysis is needed to evaluate cardiorespiratory interaction alterations in postural orthostatic tachycardia syndrome patients / B. Cairo, B. De Maria, V. Bari, F. Gelpi, M. Minonzio, F. Barbic, L.A. Dalla Vecchia, R. Furlan, A. Porta. - In: COMPUTING IN CARDIOLOGY. - ISSN 2325-887X. - 48:(2021), pp. 1-4. ((Intervento presentato al 48. convegno Computing in Cardiology 2021 tenutosi a Brno nel 2021 [10.23919/CinC53138.2021.9662712].
Abstract:
Respiratory and cardiac activities are known to be linked by several mechanisms, resulting in a variety of
patterns of heart rate variability. Cardiorespiratory interactions can be evaluated from spontaneous variability of heart period (HP) and respiration (R) through noncausal and causal approaches. The aim of this study is to describe cardiorespiratory interactions in a population known to feature an exaggerated sympathetic response to orthostatic stressors, such as patients affected by postural orthostatic tachycardia syndrome (POTS). Twelve female POTS patients (age: 36±10 yrs) and 14 female healthy controls (age: 37±8 yrs) underwent electrocardiogram and respiratory movement recordings while supine and during head-up tilt. Cardiorespiratory interactions were assessed via a model-based noncausal approach, squared coherence (K2), and a model-based causal method, transfer entropy (TE). TE was found to be significantly
decreased in POTS patients compared to healthy controls during head-up tilt, while K2 was similar. We conclude that causal approaches are better suited than noncausal methods to evaluate modifications in the magnitude of HP-R variability interactions in POTS patients during orthostatic challenge, with possible future applications in post-acute COVID-19 patients exhibiting symptoms of dysautonomia.
Tipologia IRIS:
01 - Articolo su periodico
Elenco autori:
B. Cairo, B. De Maria, V. Bari, F. Gelpi, M. Minonzio, F. Barbic, L.A. Dalla Vecchia, R. Furlan, A. Porta
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