Molecular analysis of SMARD1 patient-derived cells demonstrates that nonsense-mediated mRNA decay is impaired

Academic Article

Publication Date:

2022

Citation:

Molecular analysis of SMARD1 patient-derived cells demonstrates that nonsense-mediated mRNA decay is impaired / M. Taiana, A. Govoni, S. Salani, N. Kleinschmidt, N. Galli, M. Saladini, S.B. Ghezzi, V. Melzi, M. Bersani, R. Del Bo, O. Muehlemann, E. Bertini, V. Sansone, E. Albamonte, S. Messina, F. Mari, E. Cesaroni, L. Porfiri, F.D. Tiziano, G.L. Vita, M. Sframeli, C. Bonanno, N. Bresolin, G. Comi, S. Corti, M. Nizzardo. - In: JOURNAL OF NEUROLOGY, NEUROSURGERY AND PSYCHIATRY. - ISSN 0022-3050. - 93:8(2022 Aug), pp. 908-910. [10.1136/jnnp-2021-326425]

IRIS type:

01 - Articolo su periodico

Keywords:

motor neuron disease

List of contributors:

M. Taiana, A. Govoni, S. Salani, N. Kleinschmidt, N. Galli, M. Saladini, S.B. Ghezzi, V. Melzi, M. Bersani, R. Del Bo, O. Muehlemann, E. Bertini, V. Sansone, E. Albamonte, S. Messina, F. Mari, E. Cesaroni, L. Porfiri, F.D. Tiziano, G.L. Vita, M. Sframeli, C. Bonanno, N. Bresolin, G. Comi, S. Corti, M. Nizzardo

Authors of the University:

COMI GIACOMO PIETRO ( author )

CORTI STEFANIA PAOLA ( author )

SANSONE VALERIA ADA MARIA ( author )

Link to information sheet:

https://air.unimi.it/handle/2434/904227

Full Text:

https://air.unimi.it/retrieve/handle/2434/904227/1971986/jnnp-2021-326425.full.pdf

https://air.unimi.it/retrieve/handle/2434/904227/2187164/908.full.pdf

Project:

Assessing the pathogenetic role of tRNA and rRNA deregulation in disease-specific human and mouse models to understand pathogenesis and identify molecular therapeutics targets for Spinal Muscular Atrophy with Respiratory Distress type 1

Research Areas

Concepts

Old Academic field (valid till 24/06/2024)

Settore MED/26 - Neurologia