MANTOVANI ROBERTO


PROFESSORE ORDINARIO
Dipartimento di Bioscienze
Settori (4)
Parole Chiave (5)
EPIGENETICA
GENE EXPRESSION REGULATION
GENE-SPECIFIC GENE PROFILING
GENOMICA
TRASCRIZIONE
Ricerca Finanziata (10)
Ordina Anno:
Synergy of NF-Y with a core set of transcription factors involved in cancer signatures genes (3º anno). 
ASS_NAZ - Bandi da Associazioni e altri Finanziatori privati nazionali
Project
2019
Synergy of NF-Y with a core set of transcription factors involved in cancer signatures genes”- II ANNUALITÀ. 
ASS_NAZ - Bandi da Associazioni e altri Finanziatori privati nazionali
Project
2018
NF-YA as a molecular switch with therapeutic potential in muscle regeneration. 
INTLI - Finanziamenti internazionali
Project
2016
NF-Y and the organization of a core set of growth controlling transcription factors. 
ASS_NAZ - Bandi da Associazioni e altri Finanziatori privati nazionali
Project
2015
NF-Y and the organization of a core set of growth controlling transcription factors. 
ASS_NAZ - Bandi da Associazioni e altri Finanziatori privati nazionali
Project
2014
Dissection of pathways leading to MLL recruitment to CCAAT promoters. 
ASS_NAZ - Bandi da Associazioni e altri Finanziatori privati nazionali
Project
2010
No Results Found
Pubblicazioni (190)
Ordina Anno:
Filtra per Pubblicazioni:
Filtra per tipo accesso:
NF-YA overexpression protects from glutamine deprivation. 
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH. 
2020
Academic Article
The Switch from NF-YAl to NF-YAs Isoform Impairs Myotubes Formation. 
CELLS. 
2020
Academic Article
Open Access
NF-YA enters cells through cell penetrating peptides. 
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH. 
2019
Academic Article
Reserved Access
NF-YA overexpression in lung cancer : LUSC. 
GENES. 
2019
Academic Article
Open Access
Overexpression and alternative splicing of NF-YA in breast cancer. 
SCIENTIFIC REPORTS. 
2019
Academic Article
Open Access
The Plant NF-Y DNA Matrix In Vitro and In Vivo. 
PLANTS. 
2019
Academic Article
Open Access
Plant Flowering : Imposing DNA Specificity on Histone-Fold Subunits. 
TRENDS IN PLANT SCIENCE. 
2018
Academic Article
Reserved Access
CONSTANS imparts DNA sequence specificity to the histone fold NF-YB/NF-YC dimer. 
PLANT CELL. 
2017
Academic Article
Open Access
Nuclear factor Y in development and disease. 
BIOCHIMICA ET BIOPHYSICA ACTA. GENE REGULATORY MECHANISMS. 
2017
Academic Article
Direct non transcriptional role of NF-Y in DNA replication. 
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH. 
2016
Academic Article
NF-YA splice variants have different roles on muscle differentiation. 
BIOCHIMICA ET BIOPHYSICA ACTA. GENE REGULATORY MECHANISMS. 
2016
Academic Article
Open Access
Mode of action of trabectedin in myxoid liposarcomas. 
ONCOGENE. 
2014
Academic Article
Reserved Access
Targeting the Y/CCAAT box in cancer : YB-1 (YBX1) or NF-Y?. 
CELL DEATH AND DIFFERENTIATION. 
2013
Academic Article
YB-1 (YBX1) does not bind to Y/CCAAT boxes in vivo. 
ONCOGENE. 
2013
Academic Article
Interactions and CCAAT-binding of Arabidopsis thaliana NF-Y subunits. 
PLOS ONE. 
2012
Academic Article
Open Access
NF-Y and the transcriptional activation of CCAAT promoters. 
CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY. 
2012
Academic Article
Reserved Access
The NF-Y/p53 liaison: well beyond repression. 
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER. 
2012
Academic Article
The promiscuous life of plant NUCLEAR FACTOR Y transcription factors. 
PLANT CELL. 
2012
Academic Article
Reserved Access
miR-205 regulates basement membrane deposition in human prostate: implications for cancer development. 
CELL DEATH AND DIFFERENTIATION. 
2012
Academic Article
Reserved Access
An acetylation-mono-ubiquitination switch on lysine 120 of H2B. 
EPIGENETICS. 
2011
Academic Article
Reserved Access
NF-Y is essential for expression of the proapoptotic bim gene in sympathetic neurons. 
CELL DEATH AND DIFFERENTIATION. 
2011
Academic Article
NF-Y rectruits Ash2L to impart H3K4 trimethylation on CCAAT promoters. 
PLOS ONE. 
2011
Academic Article
Open Access
C/EBPd gene targets in human keratinocytes. 
PLOS ONE. 
2010
Academic Article
Open Access
Embryonic stem cells as an ectodermal cellular model of human p63-related dysplasia syndromes. 
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 
2010
Academic Article
The p63 target HBP1 is required for skin differentiation and stratification. 
CELL DEATH AND DIFFERENTIATION. 
2010
Academic Article
A new p63-deficient mouse model or a fresh look at an old one?. 
CELL DEATH AND DIFFERENTIATION. 
2009
Academic Article
A perspective of promoter architecture from the CCAAT box. 
CELL CYCLE. 
2009
Academic Article
Reserved Access
NF-YC complexity is generated by dual promoters and alternative splicing. 
THE JOURNAL OF BIOLOGICAL CHEMISTRY. 
2009
Academic Article
Trabectedin (ET-743) promotes differentiation in myxoid liposarcoma tumors. 
MOLECULAR CANCER THERAPEUTICS. 
2009
Academic Article
Transcriptional network of p63 in human keratinocytes. 
PLOS ONE. 
2009
Academic Article
Open Access
p63 regulates the caspase-8-Flip apoptotic pathway in epidermis. 
CELL DEATH AND DIFFERENTIATION. 
2009
Academic Article
Posttranslational regulation of NF-YA modulates NF-Y transcriptional activity. 
MOLECULAR BIOLOGY OF THE CELL. 
2008
Academic Article
The histone-like NF-Y is a bifunctional transcription factor. 
MOLECULAR AND CELLULAR BIOLOGY. 
2008
Academic Article
Open Access
DNA compaction by the nuclear factor Y (NF-Y). 
BIOPHYSICAL JOURNAL. 
2007
Academic Article
DeltaNp63 regulates thymic development through enhanced expression of FgfR2 and Jag2. 
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 
2007
Academic Article
Modulation of gene transcription by natural products -a viable anticancer strategy. 
CURRENT PHARMACEUTICAL DESIGN. 
2007
Academic Article
Modulation of topoisomerase IIalpha expression by a DNA sequence-specific polyamide. 
MOLECULAR CANCER THERAPEUTICS. 
2007
Academic Article
Reciprocal regulation of p63 by C/EBP delta in human keratinocytes. 
BMC MOLECULAR BIOLOGY. 
2007
Academic Article
Open Access
Identification of new p63 targets in human keratinocytes. 
CELL CYCLE. 
2006
Academic Article
Mechanisms of transcriptional repression of cell-cycle G2/M promoters by p63. 
NUCLEIC ACIDS RESEARCH. 
2006
Academic Article
DeltaNp63alpha up-regulates the Hsp70 gene in human cancer. 
CANCER RESEARCH. 
2005
Academic Article
Direct p53 transcriptional repression : in vivo analysis of CCAAT-containing G2/M promoters. 
MOLECULAR AND CELLULAR BIOLOGY. 
2005
Academic Article
Expression of the CCAAT-binding factor NF-Y in Caenorhabditis elegans. 
JOURNAL OF MOLECULAR HISTOLOGY. 
2005
Academic Article
Cell-cycle regulation of NF-YC nuclear localization. 
CELL CYCLE. 
2004
Academic Article
NP95 is a histone-binding protein endowed with ubiquitin ligase activity. 
MOLECULAR AND CELLULAR BIOLOGY. 
2004
Academic Article
Dynamic recruitment of NF-Y and histone acetyltransferases on cell-cycle promoters. 
THE JOURNAL OF BIOLOGICAL CHEMISTRY. 
2003
Academic Article
Interactions between p300 and multiple NF-Y trimers govern cyclin B2 promoter function. 
THE JOURNAL OF BIOLOGICAL CHEMISTRY. 
2003
Academic Article
Transcriptional activation of the cyclin A gene by the architectural transcription factor HMGA2. 
MOLECULAR AND CELLULAR BIOLOGY. 
2003
Academic Article
Open Access
Complex transcriptional effects of p63 isoforms: identification of novel activation and repression domains. 
MOLECULAR AND CELLULAR BIOLOGY. 
2002
Academic Article
Open Access
NF-Y recruitment of TFIID, multiple interactions with histone fold TAF(II)s. 
THE JOURNAL OF BIOLOGICAL CHEMISTRY. 
2002
Academic Article
Ternary complex formation between MADS-box transcription factors and the histone fold protein NF-YB. 
THE JOURNAL OF BIOLOGICAL CHEMISTRY. 
2002
Academic Article
Reserved Access
Unique features of the mode of action of ET-743. 
THE ONCOLOGIST. 
2002
Academic Article
Open Access
HSP-CBF is an NF-Y-dependent coactivator of the heat shock promoters CCAAT boxes. 
THE JOURNAL OF BIOLOGICAL CHEMISTRY. 
2001
Academic Article
Reserved Access
NF-Y mediates the transcriptional inhibition of the cyclin B1, cyclin B2, and cdc25C promoters upon induced G2 arrest. 
THE JOURNAL OF BIOLOGICAL CHEMISTRY. 
2001
Academic Article
Reserved Access
Cloning and characterization of the histone-fold proteins YBL1 and YCL1. 
NUCLEIC ACIDS RESEARCH. 
2000
Academic Article
Interference of transcriptional activation by the antineoplastic drug ecteinascidin-743. 
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 
2000
Academic Article
Open Access
Dissection of the NF-Y transcriptional activation potential. 
NUCLEIC ACIDS RESEARCH. 
1999
Academic Article
Open Access
Interactions of the CCAAT-binding trimer NF-Y with nucleosomes. 
THE JOURNAL OF BIOLOGICAL CHEMISTRY. 
1999
Academic Article
NF-Y associates with H3-H4 tetramers and octamers by multiple mechanisms. 
MOLECULAR AND CELLULAR BIOLOGY. 
1999
Academic Article
NF-Y binding to twin CCAAT boxes : role of Q-rich domains and histone fold helices. 
JOURNAL OF MOLECULAR BIOLOGY. 
1999
Academic Article
Reserved Access
NF-Y histone fold α1 helices help impart CCAAT specificity. 
JOURNAL OF MOLECULAR BIOLOGY. 
1999
Academic Article
Reserved Access
The molecular biology of the CCAAT-binding factor NF-Y. 
GENE. 
1999
Academic Article
Reserved Access
A survey of 178 NF-Y binding CCAAT boxes. 
NUCLEIC ACIDS RESEARCH. 
1998
Academic Article
Open Access
Conservation and divergence of NF-Y transcriptional activation function. 
NUCLEIC ACIDS RESEARCH. 
1998
Academic Article
Open Access
DNA binding of NF-Y : the effect of HMGI proteins depends upon the CCAAT box. 
FEBS LETTERS. 
1998
Academic Article
Reserved Access
NF-Y organizes the gamma-globin CCAAT boxes region. 
THE JOURNAL OF BIOLOGICAL CHEMISTRY. 
1998
Academic Article
Reserved Access
Synergistic activation of transcription by nuclear factor Y and sterol regulatory element binding protein. 
JOURNAL OF LIPID RESEARCH. 
1998
Academic Article
Reserved Access
Cloning and expression of human NF-YC. 
GENE. 
1997
Academic Article
Reserved Access
Cloning of Schistosoma mansoni transcription factor NF-YA subunit : phylogenic conservation of the HAP-2 homology domain. 
MOLECULAR AND BIOCHEMICAL PARASITOLOGY. 
1996
Academic Article
Reserved Access
CCAAT-box binding protein NF-Y (CBF, CP1) recognizes the minor groove and distorts DNA. 
NUCLEIC ACIDS RESEARCH. 
1995
Academic Article
Open Access
Distamycin A and tallimustine inhibit TBP binding and basal in vitro transcription. 
NUCLEIC ACIDS RESEARCH. 
1995
Academic Article
Open Access
Dominant negative analogs of NF-YA. 
THE JOURNAL OF BIOLOGICAL CHEMISTRY. 
1994
Academic Article
Reserved Access
Heterogeneity of delta, beta-thalassemia and hereditary persistence of Hb F in the Mediterranean area. 
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES. 
1985
Academic Article
Principi di genetica. 
2010
Translation
Collegi Di Dottorato (17)
Ordina Anno:
Università degli Studi di MILANO - BIOLOGIA MOLECOLARE E CELLULARE-2019 (ciclo: 35 - Anno: 2019 )
Università degli Studi di MILANO - BIOLOGIA MOLECOLARE E CELLULARE-2018 (ciclo: 34 - Anno: 2018 )
Università degli Studi di MILANO - BIOLOGIA MOLECOLARE E CELLULARE-2017 (ciclo: 33 - Anno: 2017 )
Università degli Studi di MILANO - BIOLOGIA MOLECOLARE E CELLULARE-2016 (ciclo: 32 - Anno: 2016 )
Università degli Studi di MILANO - BIOLOGIA MOLECOLARE E CELLULARE-2015 (ciclo: 31 - Anno: 2015 )
Università degli Studi di MILANO - BIOLOGIA MOLECOLARE E CELLULARE-2014 (ciclo: 30 - Anno: 2014 )
Università degli Studi di MILANO - BIOLOGIA MOLECOLARE E CELLULARE-2013 (ciclo: 29 - Anno: 2013 )
Università degli Studi di MILANO - SCUOLA DI DOTTORATO IN SCIENZE BIOLOGICHE E MOLECOLARI-2012 (ciclo: 28 - Anno: 2012 )
Università degli Studi di MILANO - SCIENZE BIOLOGICHE E MOLECOLARI-2011 (ciclo: 27 - Anno: 2011 )
Università degli Studi di MILANO - SCIENZE BIOLOGICHE E MOLECOLARI-2010 (ciclo: 26 - Anno: 2010 )
Università degli Studi di MILANO - SCIENZE BIOLOGICHE E MOLECOLARI-2009 (ciclo: 25 - Anno: 2009 )
Università degli Studi di MILANO - SCIENZE GENETICHE E BIOMOLECOLARI-2008 (ciclo: 24 - Anno: 2008 )
Università degli Studi di MILANO - SCIENZE GENETICHE E BIOMOLECOLARI-2007 (ciclo: 23 - Anno: 2007 )
Università degli Studi di MILANO - SCIENZE GENETICHE E BIOMOLECOLARI-2006 (ciclo: 22 - Anno: 2006 )
Università degli Studi di MILANO - SCIENZE GENETICHE E BIOMOLECOLARI-2005 (ciclo: 21 - Anno: 2005 )
Università degli Studi di MILANO - SCIENZE GENETICHE E BIOMOLECOLARI-2004 (ciclo: 20 - Anno: 2004 )
Università degli Studi di MILANO - SCIENZE GENETICHE E BIOMOLECOLARI-2003 (ciclo: 19 - Anno: 2003 )
No Results Found
Tutoraggio (15)
Ordina Anno:
tutorship - Assegnisti - SEMEGHINI VALENTINA (01/04/2020 - 31/03/2021)
tutorship - Dottorandi - SAAD DANA (01/10/2017 - )
tutorship - Dottorandi - LIBETTI DEBORA (01/10/2016 - 04/05/2020)
tutorship - Assegnisti - GATTA RAFFAELLA (01/07/2014 - 30/06/2016)
tutorship - Assegnisti - GATTA RAFFAELLA (01/07/2014 - 30/06/2016)
tutorship - Assegnisti - DOLFINI DILETTA (01/01/2014 - 31/12/2015)
tutorship - Dottorandi - CHIARAMONTE MARIA LUISA (01/11/2012 - 09/12/2015)
tutorship - Assegnisti - BORRELLI SERENA (01/11/2011 - 31/10/2012)
tutorship - Dottorandi - LORENZO MARIANGELA (01/11/2011 - 22/05/2015)
tutorship - Assegnisti - GATTA RAFFAELLA (01/07/2011 - 31/12/2011)
tutorship - Dottorandi - CANNAVO' ENRICO (01/01/2011 - 24/01/2014)
tutorship - Assegnisti - GATTA RAFFAELLA (01/07/2010 - 30/06/2011)
tutorship - Assegnisti - GATTA RAFFAELLA (01/07/2010 - 31/12/2011)
tutorship - Assegnisti - DOLFINI DILETTA (01/04/2010 - 31/12/2011)
tutorship - Assegnisti - BORRELLI SERENA (01/11/2009 - 31/10/2011)
No Results Found