inglese (Stati Uniti)DE FABIANI EMMA SELINA ROSA
- Contatti
- emma.defabiani@unimi.it
- Rubrica di Ateneo
DE FABIANI EMMA SELINA ROSA
Pubblicazioni (124)
Inhibition of class I histone deacetylases unveils a mitochondrial signature and enhances lipid oxidation in skeletal muscle and adipose tissue.
CHEMISTRY AND PHYSICS OF LIPIDS.2011
Abstract
Histone deacetylases modulating nuclear receptors regulate bile acid synthesis and lipid metabolism.
THE FEBS JOURNAL.2008
Abstract
Nuclear receptors, coregulators and chromatin in the control of gene regulation and cellular metabolism.
NMCD. NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES.2007
Abstract
Integration of lipid signaling and inflammatory pathways in macrophages and glial cells : a proposed role for sterol 27-hydroxylase.
ATHEROSCLEROSIS SUPPLEMENTS.2006
Abstract
Olive oil phenols modulate TNF-alpha induced matrix metalloproteinase-9 in THP-1 cells.
ATHEROSCLEROSIS SUPPLEMENTS.2006
Abstract
CYP27 is part of the cellular response to ligand-dependent activation of the nuclear receptor LXR in macrophages and glial cells.
CHEMISTRY AND PHYSICS OF LIPIDS.2005
Abstract
CYP27 transcription is modulated by regulators of the immune response and by inflammatory signals in human macrophages.
CHEMISTRY AND PHYSICS OF LIPIDS.2005
Abstract
Histone deacetylases regulate bile acid biosynthesis.
CHEMISTRY AND PHYSICS OF LIPIDS.2005
Abstract
Olive oil catechols modulate human monocyte activity.
CHEMISTRY AND PHYSICS OF LIPIDS.2005
Abstract
Inhibition of class I HDACs imprints adipogenesis toward oxidative and brown-like phenotype.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS.2020
Academic Article
Open Access
Epigenetica e patologie cardiometaboliche: nuove prospettive = Epigenetic and cardiometabolic diseases: new perspectives.
GIORNALE ITALIANO DELL'ARTERIOSCLEROSI.2019
Academic Article
Reserved Access
Epigenome modifiers and metabolic rewiring: New frontiers in therapeutics.
PHARMACOLOGY & THERAPEUTICS.2019
Academic Article
Reserved Access
Fat matters for bugs : how lipids and lipid modifications make the difference in bacterial life.
EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY.2019
Academic Article
Reserved Access
2019
Academic Article
Open Access
Mitochondrial dysfunction increases fatty acid β-oxidation and translates into impaired neuroblast maturation.
FEBS LETTERS.2019
Academic Article
Partially Open Access
A bio-guided approach for the development of a chestnut-based proanthocyanidin-enriched nutraceutical with potential anti-gastritis properties.
PHARMACOLOGICAL RESEARCH.2018
Academic Article
Partially Open Access
Gender-related metabolomics and lipidomics : from experimental animal models to clinical evidence.
JOURNAL OF PROTEOMICS.2018
Academic Article
Reserved Access
Attenuation of diet-induced obesity and induction of white fat browning with a chemical inhibitor of histone deacetylases.
INTERNATIONAL JOURNAL OF OBESITY.2017
Academic Article
Partially Open Access
HDAC3 is a molecular brake of the metabolic switch supporting white adipose tissue browning.
NATURE COMMUNICATIONS.2017
Academic Article
Open Access
Strawberry tannins inhibit IL-8 secretion in a cell model of gastric inflammation.
PHARMACOLOGICAL RESEARCH.2016
Academic Article
Reserved Access
Lack of sterol regulatory element binding factor-1c imposes glial fatty acid utilization leading to peripheral neuropathy.
CELL METABOLISM.2015
Academic Article
Reserved Access
Lipids in the nervous system : from biochemistry and molecular biology to patho-physiology.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS.2015
Academic Article
Reserved Access
Olive oil phenolic extract regulates interleukin-8 expression by transcriptional and post-transcriptional mechanisms in Caco-2 cells.
MOLECULAR NUTRITION & FOOD RESEARCH.2015
Academic Article
Reserved Access
Targeting lipid metabolism to starve and stop cancer cells.
EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY.2015
Academic Article
Energizing genetics and epi-genetics : role in the regulation of mitochondrial function.
CURRENT GENOMICS.2014
Academic Article
Reserved Access
LT175 is a novel PPARα/γ ligand with potent insulin sensitizing effects and reduced adipogenic properties.
THE JOURNAL OF BIOLOGICAL CHEMISTRY.2014
Academic Article
Lipids IN the brain : crossing the "insurmountable" barrier for a fatty, happy life.
EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY.2014
Academic Article
Reserved Access
Neuroactive steroid treatment modulates myelin lipid profile in diabetic peripheral neuropathy.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY.2014
Academic Article
Reserved Access
2014
Academic Article
2013
Academic Article
Reserved Access
Brown-like adipocytes colonizing white fat: A (r)evolutionary way to fight obesity?.
EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY.2012
Academic Article
Diabetes-induced myelin abnormalities are associated with an altered lipid pattern: protective effects of LXR activation.
JOURNAL OF LIPID RESEARCH.2012
Academic Article
Linking epigenetics to lipid metabolism: Focus on histone deacetylases.
MOLECULAR MEMBRANE BIOLOGY.2012
Academic Article
The complex world of sterols: Many threads find their way through cells.
EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY.2012
Academic Article
Liver X receptor activation protects from diabetic neuropathy by restoring fatty acid biosynthesis.
THE FEBS JOURNAL.2011
Academic Article
Spotlights on Lipid Science from the 36th FEBS Congress, June 25–30, 2011, Torino, Italy.
EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY.2011
Academic Article
The true story of palmitoleic acid : between myth and reality.
EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY.2011
Academic Article
Enterodiol and enterolactone modulate the immune response by acting on nuclear factor-kappaB (NF-kappaB) signaling.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY.2010
Academic Article
Olive Oil phenols modulate the expression of metalloproteinase 9 in THP-1 cells by acting on nuclear factor-kB signaling.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY.2010
Academic Article
Reserved Access
Oxysterols : Swiss army knife in a cell's toolbox.
EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY.2010
Academic Article
Expression of sterol 27-hydroxylase in glial cells and its regulation by liver X receptor signaling.
NEUROSCIENCE.2009
Academic Article
Improved lipid metabolism and reduced fat deposition in a mouse model of diet-induced obesity (DIO) with a new dual PPAR alpha/gamma ligand.
CHEMISTRY AND PHYSICS OF LIPIDS.2009
Academic Article
Study of 1,4-dihydropyridine structural scaffold : discovery of novel sirtuin activators and inhibitors.
JOURNAL OF MEDICINAL CHEMISTRY.2009
Academic Article
Bile acids and gene regulation : from nuclear receptors to chromatin.
FRONTIERS IN BIOSCIENCE.2008
Academic Article
Disruption of the gene encoding 3 beta-hydroxysterol Delta(14)-reductase (Tm7sf2) in mice does not impair cholesterol biosynthesis.
THE FEBS JOURNAL.2008
Academic Article
Plasma oxysterols in normal and cholestatic children as indicators of the two pathways of bile acid synthesis.
CLINICA CHIMICA ACTA.2008
Academic Article
Age-related changes in bile acid synthesis and hepatic nuclear receptor expression.
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION.2007
Academic Article
Bile acids and their signaling pathways : eclectic regulators of diverse cellular functions.
CELLULAR AND MOLECULAR LIFE SCIENCES.2007
Academic Article
Changes in classic and alternative pathways of bile acid synthesis in chronic liver disease.
CLINICA CHIMICA ACTA.2007
Academic Article
Insights in the regulation of cholesterol 7alpha-hydroxylase gene reveal a target for modulating bile acid synthesis.
HEPATOLOGY.2007
Academic Article
Nuclear receptors and coregulators in the control of cellular metabolism.
JOURNAL OF CLINICAL LIPIDOLOGY.2007
Academic Article
The pharmacological exploitation of cholesterol 7alpha-hydroxylase, the key enzyme in bile acid synthesis : from binding resins to chromatin remodelling to reduce plasma cholesterol.
PHARMACOLOGY & THERAPEUTICS.2007
Academic Article
Decreased hepatic expression of PPAR-gamma coactivator-1 in cholesterol cholelithiasis.
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION.2006
Academic Article
Minor components of olive oil modulate proatherogenic adhesion molecules involved in endothelial activation.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY.2006
Academic Article
A minimally invasive technique for the evaluation of the regulatory steps of the two major pathways of bile acid synthesis.
CLINICA CHIMICA ACTA.2005
Academic Article
2004
Academic Article
LXR (liver X receptor) and HNF-4 (hepatocyte nuclear factor-4): key regulators in reverse cholesterol transport.
BIOCHEMICAL SOCIETY TRANSACTIONS.2004
Academic Article
Lipid-activated nuclear receptors: from gene transcription to the control of cellular metabolism.
EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY.2004
Academic Article
Coordinated control of cholesterol catabolism to bile acids and of gluconeogenesis via a novel mechanism of transcription regulation linked to the fasted-to-fed cycle.
THE JOURNAL OF BIOLOGICAL CHEMISTRY.2003
Academic Article
2001
Academic Article
The negative effects of bile acids and tumor necrosis factor- on the transcription of cholesterol 7alpha-hydroxylase gene (CYP7A1) converge to hepatic nuclear factor-4. A novel mechanism of feedback regulation of bile acid synthesis mediated by nuclear receptors.
THE JOURNAL OF BIOLOGICAL CHEMISTRY.2001
Academic Article
Identification and characterisation of cis-acting elements conferring insulin-responsiveness to hamster cholesterol 7alpha-hydroxylase gene promoter.
BIOCHEMICAL JOURNAL.2000
Academic Article
Cholesta-5,7,9(11)-trien-3 beta-ol found in plasma of patients with Smith-Lemli-Opitz syndrome indicates formation of sterol hydroperoxide.
JOURNAL OF LIPID RESEARCH.1996
Academic Article
Regulation of the hamster cholesterol 7alpha-hydroxylase gene: prevalence of negative over positive transcriptional control.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS.1996
Academic Article
Plasma lipoproteins and cholesterol metabolism in Yoshida rats: an animal model of spontaneous hyperlipemia.
LIFE SCIENCES.1992
Academic Article
Effect of natural and structurally modified bile acids on cholesterol metabolizing enzymes in rat liver microsomes. II..
CHEMISTRY AND PHYSICS OF LIPIDS.1991
Academic Article
Effect of natural and structurally modified bile acids on cholesterol metabolizing enzymes in rat liver microsomes.
CHEMISTRY AND PHYSICS OF LIPIDS.1989
Academic Article
The effect of etofibrate on cholesterol and bile acid metabolism in the hamster.
PHARMACOLOGICAL RESEARCH.1989
Academic Article
ALTERATIONS IN HIGH-DENSITY LIPOPROTEIN SUBFRACTIONS DURING POSTPRANDIAL LIPIDEMIA INDUCED BY FAT WITH AND WITHOUT ETHANOL.
CLINICAL SCIENCE.1988
Academic Article
Single dose pharmacokinetics of aminoglutethimide by a rapid SIM methodology.
INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY THERAPY AND TOXICOLOGY.1988
Academic Article
Effect of tauroursodeoxycholate feeding, with or without taurine supplementation on hepatic bile acid and cholesterol metabolism in the hamster.
PHARMACOLOGICAL RESEARCH COMMUNICATIONS.1987
Academic Article
Taurine increases bile acid pool size and reduces bile saturation index in the hamster.
JOURNAL OF LIPID RESEARCH.1987
Academic Article
1999
Chapter
Activation of the liver x receptors ameliorates diabetic peripheral neuropathy increasing locally neuroactive steroid levels.
THE FEBS JOURNAL.2011
Conference Poster
Reserved Access
2011
Conference Poster
Reserved Access
Generation of a liver-specific HDAC7 KO mouse model and effect of selective HDAC inhibitors on cholesterol 7α-hydroxylase gene in mice.
THE FEBS JOURNAL.2011
Conference Poster
Reserved Access
Involvement of histone deacetylases (HDAC) in the molecular regulatory pathway of cholesterol 7α-hydroxylase: an in vitro approach with selective HDAC inhibitors.
THE FEBS JOURNAL.2011
Conference Poster
Reserved Access
Study of the mechanism of action of LT175, a dual PPAR ligand that ameliorates the metabolic profile and insulin sensitivity in different mouse models.
THE FEBS JOURNAL.2011
Conference Poster
Reserved Access
The effect of the liver x receptors activation on neuroactive steroids levels in the central nervous system of diabetic rats.
THE FEBS JOURNAL.2011
Conference Poster
Reserved Access
2010
Conference Poster
Deacetylase inhibitors modulate mitochondrial biogenesis in skeletal muscle.
THE FASEB JOURNAL.2010
Conference Poster
OLIVE OIL PHENOLS MODULATE THE EXPRESSION OF METALLOPROTEINASE 9 IN A MONOCYTIC CELL LINE BY ACTING ON NF-KB SIGNALLING.
ATHEROSCLEROSIS SUPPLEMENTS.2009
Conference Poster
Effects of histone deacetylase inhibitors on energy metabolism.
CHEMISTRY AND PHYSICS OF LIPIDS.2007
Conference Poster
Hepatic nuclear receptor expression and metabolism of cholesterol and bile acids in humans.
JOURNAL OF CLINICAL LIPIDOLOGY.2007
Conference Poster
Inhibition of platelet aggregation and cAMP- and cGMP-phosphodiesterases by olive oil phenols.
ITALIAN JOURNAL OF BIOCHEMISTRY.2007
Conference Poster
Nuclear receptors, coregulators and chromatin in the control of gene regulation and cellular metabolism.
ITALIAN JOURNAL OF BIOCHEMISTRY.2007
Conference Poster
Analysis of nuclear factors dynamically exchanged on the cholesterol 7 alpha-hydroxylase gene reveals a target for treatment of hypercholesterolemia.
CHEMISTRY AND PHYSICS OF LIPIDS.2006
Conference Poster
Bile acids repress cholesterol 7 alpha-hydroxylase gene transcription by recruiting histone deacetylases.
FASEB JOURNAL.2006
Conference Poster
Bile acids repress cholesterol 7 alpha-hydroxylase gene transcription by recruiting histone deacetylases.
THE FASEB JOURNAL.2006
Conference Poster
Differential expression and regulation of genes involved in cholesterol metabolism in brain cells.
CHEMISTRY AND PHYSICS OF LIPIDS.2006
Conference Poster
Hepatic expression of PPAR-gamma coactivator 1 (PGC-1) is reduced in human cholelithiasis.
JOURNAL OF HEPATOLOGY.2006
Conference Poster
Identification of histone deacetylase 7 as a new target for treatment of hypercholesterolemia.
ATHEROSCLEROSIS SUPPLEMENTS.2006
Conference Poster
Nuclear factor of activated T-cells (next) couples innate immunity programming to cholesterol metabolism in monocyte-macrophages.
ATHEROSCLEROSIS SUPPLEMENTS.2006
Conference Poster
The recruitment of histone deacetylases induced by bile acids inhibits trascription of cholesterol 7alpha-hydroxylase gene (CYP7A1).
ATHEROSCLEROSIS SUPPLEMENTS.2006
Conference Poster
Minor components of olive oil affect the expression of pro-atherogenic molecules and cGMP-dependent PDE5 activity.
CHEMISTRY AND PHYSICS OF LIPIDS.2004
Conference Poster
Olive oil phenols: antioxidant activity and beyond.
CHEMISTRY AND PHYSICS OF LIPIDS.2004
Conference Poster
In vivo evaluation of the two metabolic pathways of cholesterol catabolism in normal human subjects and in patients with liver disease.
JOURNAL OF HEPATOLOGY.2003
Conference Poster
2002
Conference Poster
2016
Document
Reserved Access
2015
Document
Reserved Access
2014
Document
Reserved Access
2014
Document
Reserved Access
2012
Document
2008
Document
2014
Thesis
Open Access
Comitati Editoriali
Direttore di rivista, collana editoriale, enciclopedia - EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY (2010 - )
2010
No Results Found
Collegi Di Dottorato (16)
Università degli Studi di MILANO -
SCIENZE FARMACOLOGICHE BIOMOLECOLARI, SPERIMENTALI E CLINICHE-2019
(ciclo: 35 - Anno: 2019
2019
)
Università degli Studi di MILANO -
SCIENZE FARMACOLOGICHE BIOMOLECOLARI, SPERIMENTALI E CLINICHE-2018
(ciclo: 34 - Anno: 2018
2018
)
Università degli Studi di MILANO -
SCIENZE BIOCHIMICHE-2017
(ciclo: 33 - Anno: 2017
2017
)
Università degli Studi di MILANO -
SCIENZE BIOCHIMICHE-2016
(ciclo: 32 - Anno: 2016
2016
)
Università degli Studi di MILANO -
SCIENZE BIOCHIMICHE-2015
(ciclo: 31 - Anno: 2015
2015
)
Università degli Studi di MILANO -
SCIENZE BIOCHIMICHE-2014
(ciclo: 30 - Anno: 2014
2014
)
Università degli Studi di MILANO -
SCIENZE BIOCHIMICHE-2013
(ciclo: 29 - Anno: 2013
2013
)
Università degli Studi di MILANO -
BIOCHIMICA-2012
(ciclo: 28 - Anno: 2012
2012
)
Università degli Studi di MILANO -
BIOCHIMICA-2011
(ciclo: 27 - Anno: 2011
2011
)
Università degli Studi di MILANO -
BIOCHIMICA-2010
(ciclo: 26 - Anno: 2010
2010
)
Università degli Studi di MILANO -
BIOCHIMICA-2008
(ciclo: 24 - Anno: 2008
2008
)
Università degli Studi di MILANO -
BIOCHIMICA-2007
(ciclo: 23 - Anno: 2007
2007
)
Università degli Studi di MILANO -
BIOCHIMICA-2006
(ciclo: 22 - Anno: 2006
2006
)
Università degli Studi di MILANO -
BIOCHIMICA-2005
(ciclo: 21 - Anno: 2005
2005
)
Università degli Studi di MILANO -
BIOCHIMICA-2004
(ciclo: 20 - Anno: 2004
2004
)
Università degli Studi di MILANO -
BIOCHIMICA-2003
(ciclo: 19 - Anno: 2003
2003
)
No Results Found
Tutoraggio
tutorship -
Dottorandi
- BRIOSCHI ELISABETTA
(01/01/2011 - 27/02/2014)
20110101
No Results Found