Overview
Contributors
RICAGNO STEFANO
Scientific Manager
Departments involved
Dipartimento di Bioscienze
Principale
Type
PRIN2020 - PRIN bando 2020
Funder
MINISTERO DELL'ISTRUZIONE E DEL MERITO
External Organization Funding Organization
Date/time interval
April 25, 2022 - April 24, 2025
Project duration
36 months
Research Areas
Concepts
Publications
Outputs (9)
2025
Academic Article
Open Access
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Structural characterization of atrial natriuretic peptide amyloid fibrils from patients with atrial fibrillation
NATURE COMMUNICATIONSNATURE RESEARCH
2025
Academic Article
Open Access
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The critical role of the variable domain in driving proteotoxicity and aggregation in full-length light chains
JOURNAL OF MOLECULAR BIOLOGYELSEVIER
2025
Academic Article
Open Access
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Helical superstructures between amyloid and collagen in cardiac fibrils from a patient with AL amyloidosis
NATURE COMMUNICATIONSNATURE PUBLISHING GROUP
2024
Academic Article
Open Access
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Site-directed mutagenesis reveals the interplay between stability, structure, and enzymatic activity in RidA from Capra hircus
PROTEIN SCIENCEWILEY ONLINE LIBRARY
2024
Academic Article
Partially Open Access
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Nanobodies counteract the toxicity of an amyloidogenic light chain by stabilizing a partially open dimeric conformation
JOURNAL OF MOLECULAR BIOLOGYELSEVIER
2023
Academic Article
Partially Open Access
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The Cryo-EM structure of renal amyloid fibril suggests structurally homogeneous multiorgan aggregation in AL amyloidosis
JOURNAL OF MOLECULAR BIOLOGYELSEVIER SCIENCE LIMITED
2023
Academic Article
Partially Open Access
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Cryo-EM structure of ex vivo fibrils associated with extreme AA amyloidosis prevalence in a cat shelter
NATURE COMMUNICATIONSSPRINGER NATURE
2022
Academic Article
Open Access
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Fragment-based computational design of antibodies targeting structured epitopes
SCIENCE ADVANCESAMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE’S (AAAS)
2022
Academic Article
Open Access
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