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Application of CRISPR-based Prime Editing as a modeling tool to unveil the pathomechanisms of Vanishing White Matter disease
Project
Overview
Publications
Overview
Contributors
RICCIARDI SARA
Scientific Manager
Departments involved
Dipartimento di Bioscienze
Principale
Type
Progetti PNRR - Fondo per il Programma di Ricerca di Rilevante Interesse Nazionale - PRIN 2022
Funder
MINISTERO DELL'UNIVERSITA' E DELLA RICERCA
External Organization
Funding Organization
Date/time interval
November 30, 2023 - February 28, 2026
Project duration
27 months
Publications
Outputs
Prime editing links the split integrated stress response to pathogenic eIF2B mutations and white matter degeneration
CELL DEATH & DISEASE
SPRINGER
2026
Academic Article
Open Access
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