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CD34+ LP-1R+hematopoietic stem/progenitor cell subpopulation: a novel cellular target in cardiovascular disease

Project
La caratterizzazione fenotipica, funzionale e farmacologica di una sottopopolazione di cellule staminali ematopoietiche caratterizzate dall’espressione del recettore per il glucagon-like peptide 1 (GLP1), caratteristica che conferisce alla popolazione cellulare un fenotipo protettivo a livello cardiovascolare.
  • Academic Signature
  • Overview
  • Research Areas
  • Publications

Academic Signature

Il servizio di classificazione ACADEMIC SIGNATURE è IN BETA TESTING e i risultati potrebbero non essere corretti

Academic Signature

Glucagon-Like Peptide-1 Receptor
Glucagon-Like Peptide Receptors

Overview

Contributors

SIRONI LUIGI   Scientific Manager  

Departments involved

Dipartimento di Scienze Farmaceutiche   Principale  

Type

MIS - Bandi Ministero Salute

Funder

MINISTERO DELLA SALUTE
External Organization Funding Organization

Date/time interval

April 30, 2023 - April 29, 2026

Project duration

36 months

Research Areas

Concepts


Settore BIO/14 - Farmacologia

Publications

Outputs (4)

Metabolic and immune dysfunction at the crossroads between type 1 diabetes and neurodegeneration 
METABOLISM, CLINICAL AND EXPERIMENTAL
W.B. SAUNDERS; ELSEVIER
2026
Academic Article
Reserved Access
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TMEM219 signaling promotes intestinal stem cell death and exacerbates colitis 
THE JOURNAL OF CLINICAL INVESTIGATION
AMERICAN SOCIETY FOR CLINICAL INVESTIGATION
2025
Academic Article
Open Access
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Targeting of the IGFBP3/TMEM219 pathway restores intestinal stem cells capability of healing mucosa in gastrointestinal autoimmune disorders 
PHARMACOLOGICAL RESEARCH
ELSEVIER LTD
2025
Academic Article
Open Access
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Vaccinome landscape in nearly 620 000 patients with diabetes 
THE JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM
OXFORD UNIVERSITY PRESS
2025
Academic Article
Open Access
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