Drug repurposing of ERK inhibitors to target the transcription factor Nfix in dystrophic muscles: development of a new proof-of-concept study to hinder Muscular Dystrophies (3° anno)

Project

Overview

Contributors

MESSINA GRAZIELLA   Scientific Manager  

Departments involved

Dipartimento di Bioscienze   Principale  

Type

INTLI - Finanziamenti internazionali

Funder

AFM-TELETHON - ASS. FRANCAISE CONTRE LES MYOPATHIES
External Organization Funding Organization

Date/time interval

January 10, 2023 - January 9, 2024

Project duration

12 months

Research Areas

Concepts


Settore BIO/17 - Istologia

Publications

Outputs

MEK-inhibitors decrease Nfix in muscular dystrophy but induce unexpected calcifications, partially rescued with Cyanidin diet 
ISCIENCE
ELSEVIER
2024
Academic Article
Open Access
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