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Colchicine for Amyotrophic Lateral Sclerosis: a phase II, randomized, double blind, placebo controlled, multicenter clinical trial (Co-ALS)

Project
  • Overview
  • Research Areas
  • Publications

Overview

Contributors

POLETTI ANGELO   Scientific Manager  

Departments involved

Dipartimento di Scienze Farmacologiche e Biomolecolari Rodolfo Paoletti   Principale  

Type

AL_RIC - Bandi da altri enti di ricerca

Funder

AGENZIA ITALIANA DEL FARMACO - AIFA
External Organization Funding Organization

Date/time interval

September 19, 2018 - September 18, 2020

Project duration

24 months

Research Areas

Concepts


Settore BIO/13 - Biologia Applicata

Publications

Outputs (5)

Colchicine treatment in amyotrophic lateral sclerosis: safety, biological and clinical effects in a randomized clinical trial 
BRAIN COMMUNICATIONS
OXFORD UNIVERSITY PRESS
2024
Academic Article
Open Access
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Lysosomes Dysfunction Causes Mitophagy Impairment in PBMCs of Sporadic ALS Patients 
CELLS
MDPI
2022
Academic Article
Open Access
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Missense mutation in ATXN2 gene (c.2860C > T) in an amyotrophic lateral sclerosis patient with aggressive disease phenotype 
NEUROLOGICAL SCIENCES
SPRINGER-VERLAG ITALIA S.R.L.
2022
Academic Article
Reserved Access
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RNA molecular signature profiling in PBMCs of sporadic ALS patients: HSP70 overexpression is associated with nuclear SOD1 
CELLS
MDPI
2022
Academic Article
Open Access
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Proteostasis and ALS : protocol for a phase II, randomised, double-blind, placebo-controlled, multicentre clinical trial for colchicine in ALS (Co-ALS) 
BMJ OPEN
2019
Academic Article
Open Access
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