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Next Generation Biomimetic Analytical Platforms. Building Blocks for Ubiquitous Environmental Sensor Networks

Project
GOALS:
The current state-of-the-art for autonomous environmental instruments monitoring the chemical and biological status of our water is based on flow systems that employ conventional approaches to sample/liquid handling, which makes them prohibitively expensive (often >€20K per unit) in terms of up-scaling deployments. This project will investigate ways to deliver revolutionary advances in liquid/sample handling combined with new approaches to performing sensitive in-situ analytical measurements. Our goal is to drive down the unit cost of these instruments by orders of magnitude to levels that can create a tipping point, at which the technology becomes ubiquitous.

OUTCOMES:
¿ Novel technologies that will contribute significantly to the realization of next generation autonomous analytical instruments for distributed environmental monitoring.
¿ New services based on the information generated by these instruments in real deployment scenarios.
¿ Photoactuated polymer valve structures fully integrated within microfluidic channels
¿ Highly sensitive detector integrated with microfluidics sample preparation
¿ Photocontrolled functions such as filtering, preconcentration, uptake and release, surface activation/passivation

Prototype components will be integrated with existing autonomous sensing devices, and after lab based trials deployed at wastewater treatment plants and in the general environment. This strategy will enable risk to be managed by testing the novel biomimetic fluid handling components with existing detectors (e.g. colorimetric methods for nutrients). In a similar manner, a novel E coli sensor will be assessed using validated fluid handling technologies in the existing devices. This strategy will allow the biomimetic fluid handling and advanced detector elements of the research programme to advance independently, or collaboratively, depending on progress.
  • Overview
  • Publications

Overview

Contributors

BUSCAGLIA MARCO   Scientific Manager  

Departments involved

Dipartimento di Biotecnologie Mediche e Medicina Traslazionale   Principale  

Type

7PQCP-CSA - 7 Programma Quadro_Collaborative Project/Network/Coordination and Support Action

Funder

EUROPEAN COMMISSION
External Organization Funding Organization

Date/time interval

December 1, 2013 - May 31, 2017

Project duration

42 months

Publications

Outputs (9)

A microfluidic column of water index-matched packed microspheres for label-free observation of water pollutants 
MIKROCHIMICA ACTA
SPRINGER
2021
Academic Article
Partially Open Access
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Fabrication and Optical Modeling of Micro‐Porous Membranes Index‐Matched with Water for On‐Line Sensing Applications 
MACROMOLECULAR MATERIALS AND ENGINEERING
WILEY
2020
Academic Article
Partially Open Access
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Phantom membrane microfluidic cross-flow filtration device for the direct optical detection of water pollutants 
SENSORS AND ACTUATORS. B, CHEMICAL
ELSEVIER
2018
Academic Article
Partially Open Access
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Emerging applications of label-free optical biosensors 
NANOPHOTONICS
DE GRYTER OPEN
2017
Academic Article
Open Access
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Label-free detection of DNA single-base mismatches using a simple reflectance-based optical technique 
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
ROYAL SOCIETY OF CHEMISTRY
2016
Academic Article
Open Access
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Selective adsorption on fluorinated plastic enables the optical detection of molecular pollutants in water 
PHYSICAL REVIEW APPLIED
AMERICAN PHYSICAL SOCIETY
2016
Academic Article
Partially Open Access
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A fast and simple label-free immunoassay based on a smartphone 
BIOSENSORS & BIOELECTRONICS
2014
Academic Article
#internalNetwork Access
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Label-free optical detection of molecular and cellular binding on reflectionless glass 
CHEMICAL AND BIOLOGICAL MICROSYSTEMS SOCIETY
2016
Conference Paper
Reserved Access
Phantom microbeads chromatography column in microfluidics 
CHEMICAL AND BIOLOGICAL MICROSYSTEMS SOCIETY
2016
Conference Paper
Reserved Access
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