MITRO NICO

PERSONAL INFORMATION
Family name, First name: Mitro, Nico
Date of birth: May 16, 1976
Researcher unique identifier(s): ORCID ID 0000-0002-5000-3619; Scopus Author ID 6506384818.
Nationality: Italian
URL for web site: http://www.unimi.it/chiedove/ENG/schedaPersonaXML.jsp?matricola=15651

• EDUCATION
2006 – 2008: Post-doctoral fellow, Department of Chemical Physiology and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA, USA. Supervisor: Dr. Enrique Saez.
2005 – 2006: Post-doctoral fellow, Genomics Institute of the Novartis Research Foundation, San Diego, CA, USA. Supervisor: Dr. Enrique Saez.
2001 – 2006: Ph.D. in Experimental medicine: atherosclerosis, School of Medicine, Università degli Studi di Siena, Italy. Supervisor: Prof. Maurizio Crestani.
1995 – 2001: Degree in Pharmaceutical Biotechnology, School of Pharmacy, Università degli Studi di Milano, Italy.

• CURRENT POSITION(S)
2015 – To date: Associate Professor of Biochemistry, Department of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, Italy

• PREVIOUS POSITIONS
2011 – 2015: Assistant Professor, Department of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, Italy.
2008 – 2011: Principal Investigator of the Armenise-Harvard Foundation Career Development Award, Department of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, Milano,Italy.

• FELLOWSHIPS AND AWARDS
2020 – 2023: European Foundation for the Study of Diabetes (amount funded: 100.000 Euro)
2020 – 2024: Italian Association for Cancer Research (amount funded: 1.076.000 Euro)
2016 – 2019: European Foundation for the Study of Diabetes (amount funded: 100.000 Euro)
2015 – 2019: Cariplo Foundation Biomedical Research Conducted by Young Researchers (amount funded: 249.700 Euro).
2015: European Society for Neurochemistry Young Lectureship Award.
2010: Fellowship from the Italian Society of Biochemistry and Molecular Biology (SIB) for a research period at The Scripps Research Institute, La Jolla, CA, USA.
2009: Astrazeneca Award as best oral presentation at 23rd National Congress of the Italian Society for the Study of Atherosclerosis (SISA). Roma, November 25-28, 2009.
2009: Galeno Prize as Best Young Investigator.
2008: “Giovanni Galli” Prize for the Study of Atherosclerosis. Italian Society for the Study of Atherosclerosis (SISA).
2008 – 2013: Armenise-Harvard Foundation Career Development Award (amount funded: 1.000.000 $).
2006 – 2008: American Heart Association post-doctoral fellowship (amount funded: 86.000 $)
2006: Best Researcher of the Year of the Genomics Institute of the Novartis Research Foundation, San Diego, CA, USA.
2004: “Young Researcher Award” at the 15th International Symposium on Drugs Affecting Lipid Metabolism (DALM), Venice, Italy. October 24-27, 2004.
2004: Best Poster at the 49th National Meeting of the Italian Society for Biochemistry and Molecular Biology (SIB), Riccione, Italy. September 28 – October 1, 2004.
2003: Best Young Researcher for Atherosclerosis. Italian Society for the Study of Atherosclerosis (SISA).

• SUPERVISION OF GRADUATE STUDENTS AND POSTDOCTORAL FELLOWS
2008 – To date: 6 Post-doc/ 4 Ph.D. student/ 33 Master students. Department of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, Italy.

• RESEARCH ACTIVITIES
Dr. Mitro's research activity is carried out through the conception, practical implementation and analysis and interpretation of the results of the experiments. The experimental work conducted by Dr. Mitro is part of the study of lipid, glucose, amino acids and energy metabolism with the primary aim of understanding the role of metabolic regulators, both in physiological and pathological conditions. Currently Dr. Mitro's research activity is focused on the molecular mechanisms that control mitochondrial functionality. In the development of projects, Dr. Mitro applies cutting-edge technologies in the field of genomics, metabolomics and bioinformatics analysis.

• PUBLICATIONS AND BIBLIOMETRIC PARAMETERS (according to Web of Science)
A complete list of my publications can be found at orcid.org or www.scopus.com by searching the authors using the following ORCID ID 0000-0002-5000-3619 and Scopus Author ID 6506384818, respectively. Main ERC field: LS_1 Molecules of Life: Biological Mechanisms, Structures and Functions-Molecular Biology and Biochemistry.
Total publications in peer-reviewed journal: 112
(first author: 11, last and corresponding author: 19)
Research articles: 85; Reviews: 27; Book chapters: 3
h-index: 36
Citations (excluding self-citations): 3739
More than 80% of publications in the Q1 quartile
Total impact factor: 805.3
Average impact factor of first/corresponding
publications (excluding reviews): 8.9

• ON-GOING RESEARCH GRANTS
10/2020 to 09/2023: European Foundation for the Study of Diabetes (EFSD). Title of the project: “Dissecting the role of Zc3h10 in adipose tissues: a new player in type 2 diabetes onset/progression”. Role: Principal Investigator. Amount funded: 100.000€
01/2020 to 01/2026: Italian Association for Cancer Research (AIRC)-Individual Grant-2019. Title of the project: “An integrative approach for the systematic characterization of mitochondrial regulators in hepatocellular carcinoma”. Role: Principal Investigator. Amount funded: 1.076.000€
01/2020 to 12/2022: Regional Foundation for Biomedical Research (FRRB-Regione Lombardia). Title of the project: “An integrated omics approach for patients with rare neurological disorders: towards personalized clinical care and trial readiness”. Role: Head of research unit. Amount funded: 3.500.000€ (433.300€ to Nico Mitro unit).

• SELECTED INVITED PRESENTATIONS AT NATIONAL AND INTERNATIONAL CONFERENCES
In the last ten years Dr. Mitro has been invited to more than 25 National and Intenational conferences.

• PATENTS
1. "New synthetic ligands of PPARalpha and gamma for the therapy of diabetes and atherosclerosis" (2004). Patent number: MI2004A000405.
2. "A new hypocholesterolemic approach mediated by the upregulation of cholesterol 7-alpha hydroxylase gene transcription" (2005). Patent number: WO2005105066.

• ORGANISATION OF SCIENTIFIC MEETINGS
2019: Organizer and Chair of the European Society for Neurochemistry Biennial Conference “Molecular Mechanisms of Regulation of the Nervous System”. Milan, September 1-4. (about 300 participants).
2017: Organizer of the Symposium “Regulatory pathways of organelles affecting CNS and PNS pathophysiology” at the ISN-ESN International meeting. Paris, August 20-24 (about 800 participants).
2013: Member of the local organizing committee of the 54th International Conference on the Bioscience of Lipids. Bari, September 17-22. (about 300 participants).
2005: Member of the local organizing committee of the 3rd International Symposium on PPARs Efficacy and Safety: from basic science to clinical applications, Monte Carlo, March 19-23 (about 800 participants).
Every two years from 2011 Member of the local organizing committee of the International meeting on Neurosteroids and Nervous System. Torino. (about 200 participants).

• INSTITUTIONAL RESPONSIBILITIES
2019 – To date: Nominated member of the Doctoral School Committee in Pharmacological biomolecular sciences, experimental and clinical of the Università degli Studi di Milano, Italy
2013 – 2020: Nominated member of the Doctoral School Committee in Biochemical Sciences of the Università degli Studi di Milano, Italy
2011 – To date: Nominated faculty member based on competitive examination, Department of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, Italy.

• COMMISSIONS OF TRUST
2017 – To date: Elected member of the Council of European Society for Neurochemistry (ESN).
2015 – To date: Elected member of the governing board of Italian Society for the Study of Atherosclerosis (SISA) – Lombardy section.

• REVIEWING ACTIVITIES
Reviewer of grants and/or fellowships for the following agencies: Italian Ministry of Education, University and Research (MIUR), Diabetes UK, the French National Research Agency (ANR) and Dutch Research Council.
Reviewer for Nature Metabolism, Nature Communication, Cell Metabolism, EMBO Reports, Journal of Cell Biology, Biochimica et Biophysica Acta-Bioenergetics and Biochimica et Biophysica Acta-Molecular and Cell Biology of Lipids and many others.

• MEMBERSHIPS OF SCIENTIFIC SOCIETIES
2015 – To date European Society for Neurochemistry (ESN)
2013 – To date Federation of European Neuroscience Societies (FENS)
2012 – To date European Association for the Study of Diabetes (EASD)
2004 – To date Federation of European Biochemical Societies (FEBS)
2004 – To date Italian Society of Biochemistry and Molecular Biology (SIB)
2001 – To date Italian Society for the Study of Atherosclerosis (SISA)

• COLLABORATIONS
Dr. M. Crestani, A. Maggi, R. C. Melcangi, M. Di Luca, A.L. Catapano, Università degli Studi di Milano, Milano, Italy. Dr. V. Tiranti, Carlo Besta Neurological Institute, IRCCS, Milano, Italy, Dr. L. Scorrano, Dr. M. Santoro, Dr. G. Martello, Dr. S. Dupont, Università degli Studi di Padova, Padova, Italy. Dr. G. Del Sal Università degli Studi di Trieste, Trieste, Italy; Dr. K. Aquilano, Università di Roma Tor Vergata, Roma, Italy; Dr. T. Bonaldi, Dr. G. Natoli, Dr. B. Amati, Dr. P.P. Di Fiore, Dr. P.G. Pelicci IEO, Milano, Italy. Dr. V. Costanzo, IFOM, Milano, Italy; Dr. C. Taveggia HSR Research, Milano, Italy; Dr. D. Di Bernardo; Dr. N. Brunetti; A. Indrieri TIGEM, Pozzuoli, Italy; Dr. L. Lanzetti Candiolo Cancer Institute, Torino, Italy. Dr. E. Saez, The Scripps Research Institute, La Jolla, CA, USA; Dr. L. M. Garcia-Segura, Instituto Cajal, C.S.I.C., Madrid, Spain; J. Hirrlinger, Leipzig, Germany.