REGIOSELECTIVITY AND ENANTIOSELECTIVITY OF PSEUDOMONAS-CEPACIA LIPASE IN THE TRANSESTERIFICATION OF 2-SUBSTITUTED-1,4-BUTANEDIOLS
Academic Article
Publication Date:
1994
Citation:
REGIOSELECTIVITY AND ENANTIOSELECTIVITY OF PSEUDOMONAS-CEPACIA LIPASE IN THE TRANSESTERIFICATION OF 2-SUBSTITUTED-1,4-BUTANEDIOLS / P. FERRABOSCHI, P. GRISENTI, A. MANZOCCHI, E. SANTANIELLO. - In: TETRAHEDRON-ASYMMETRY. - ISSN 0957-4166. - 5:4(1994), pp. 691-698. [10.1016/0957-4166(94)80031-6]
abstract:
The transesterification of 2-substituted-1,4-butanediols 1a, 2a and 3a with vinyl acetate catalyzed by the Pseudomonas cepacia lipase in organic solvents affords preferentially the 1-acetate, the highest regioselectivity having been found for the epoxydiol 3a, which is enantioselectively resolved [86% ee for the unreacted (S)-(-)-3a].
IRIS type:
01 - Articolo su periodico
List of contributors:
P. FERRABOSCHI, P. GRISENTI, A. MANZOCCHI, E. SANTANIELLO
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