Dipartimenti di Eccellenza 2018-2022 - Dipartimento di SCIENZE FARMACOLOGICHE E BIOMOLECOLARI

Progetto

Dati Generali

Partecipanti

CORSINI ALBERTO   Responsabile scientifico  

Dipartimenti coinvolti

Tipo

DECC - Bando Dipartimenti di Eccellenza

Finanziatore

MINISTERO DELL'ISTRUZIONE E DEL MERITO
Organizzazione Esterna Ente Finanziatore

Periodo di attività

Gennaio 1, 2018 - Dicembre 31, 2022

Durata progetto

60 mesi

Pubblicazioni

Pubblicazioni (62)

Investigating ellagitannins from strawberry (Fragaria × ananassa Duch.) as a new strategy to counteract H. pylori infection and inflammation 
FOOD & FUNCTION
ROYAL SOCIETY OF CHEMISTRY
2025
Articolo
Open Access
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Vibration Rather than Microgravity Affects Bone Metabolism in Adult Zebrafish Scale Model 
CELLS
MDPI
2024
Articolo
Open Access
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Characterization of color, phenolic profile, and antioxidant activity of Italian pigmented rice varieties after different technological treatments 
FOOD BIOSCIENCE
ELSEVIER
2023
Articolo
Open Access
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Effect of Fc core fucosylation and light chain isotype on IgG1 flexibility 
COMMUNICATIONS BIOLOGY
NATURE
2023
Articolo
Open Access
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Ellagitannins from Castanea sativa Mill. Leaf Extracts Impair H. pylori Viability and Infection-Induced Inflammation in Human Gastric Epithelial Cells 
NUTRIENTS
MDPI
2023
Articolo
Open Access
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Functional Heterodimerization between the G Protein-Coupled Receptor GPR17 and the Chemokine Receptors 2 and 4: New Evidence 
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
MDPI
2023
Articolo
Open Access
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HSPB8 frameshift mutant aggregates weaken chaperone-assisted selective autophagy in neuromyopathies 
AUTOPHAGY
TAYLOR AND FRANCIS LTD.
2023
Articolo
Open Access
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Investigating the Molecular Mechanisms Underlying Early Response to Inflammation and Helicobacter pylori Infection in Human Gastric Epithelial Cells 
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
MDPI
2023
Articolo
Open Access
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Liver-directed gene therapy for ornithine aminotransferase deficiency 
EMBO MOLECULAR MEDICINE
WILEY EUROPE
2023
Articolo
Open Access
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Necroptosis Induced by Delta-Tocotrienol Overcomes Docetaxel Chemoresistance in Prostate Cancer Cells 
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
MDPI
2023
Articolo
Open Access
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Sustained IP3-linked Ca2+ signaling promotes progression of triple negative breast cancer cells by regulating fatty acid metabolism 
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
FRONTIERS MEDIA S.A.
2023
Articolo
Open Access
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Unraveling the Peculiar Features of Mitochondrial Metabolism and Dynamics in Prostate Cancer 
CANCERS
MDPI
2023
Articolo
Open Access
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A Novel Loss-of-Function SEMA3E Mutation in a Patient with Severe Intellectual Disability and Cognitive Regression 
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
MDPI
2022
Articolo
Open Access
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Alterations of mitochondrial dynamics in serotonin transporter knockout rats: A possible role in the fear extinction recall mechanisms 
FRONTIERS IN BEHAVIORAL NEUROSCIENCE
FRONTIERS RESEARCH FOUNDATION
2022
Articolo
Open Access
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Anti-Inflammatory and Anti-Acne Effects of Hamamelis virginiana Bark in Human Keratinocytes 
ANTIOXIDANTS
MDPI
2022
Articolo
Open Access
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Effects of early life stress on brain cytokines: A systematic review and meta-analysis of rodent studies 
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
ELSEVIER SCIENCE LIMITED
2022
Articolo
Open Access
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In silico investigation on structure–function relationship of members belonging to the human SLC52 transporter family 
PROTEINS
WILEY
2022
Articolo
Partially Open Access
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LSEA Evaluation of Lipid Mediators of Inflammation in Lung and Cortex of Mice Exposed to Diesel Air Pollution 
BIOMEDICINES
MDPI
2022
Articolo
Open Access
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Maternal AA/EPA Ratio and Triglycerides as Potential Biomarkers of Patients at Major Risk for Pharmacological Therapy in Gestational Diabetes 
NUTRIENTS
MDPI
2022
Articolo
Open Access
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Metabolic Profile Variations along the Differentiation of Human-Induced Pluripotent Stem Cells to Dopaminergic Neurons 
BIOMEDICINES
MDPI
2022
Articolo
Open Access
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Modulation of Glia Activation by TRPA1 Antagonism in Preclinical Models of Migraine 
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
MDPI
2022
Articolo
Open Access
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Molecular Mechanisms of Cancer Drug Resistance: Emerging Biomarkers and Promising Targets to Overcome Tumor Progression 
CANCERS
MDPI
2022
Articolo
Open Access
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Molecular Modelling of NONO and SFPQ Dimerization Process and RNA Recognition Mechanism 
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
MDPI
2022
Articolo
Open Access
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Molecular mechanisms and genetic alterations in prostate cancer: From diagnosis to targeted therapy 
CANCER LETTERS
ELSEVIER
2022
Articolo
Partially Open Access
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Pancreatic PCSK9 controls the organization of the β-cell secretory pathway via LDLR-cholesterol axis 
METABOLISM, CLINICAL AND EXPERIMENTAL
ELSEVIER
2022
Articolo
Reserved Access
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Regulatory mechanisms of the early phase of white adipocyte differentiation : an overview 
CELLULAR AND MOLECULAR LIFE SCIENCES
SPRINGER
2022
Articolo
Open Access
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Short- and Long-Term Effects of Suboptimal Selenium Intake and Developmental Lead Exposure on Behavior and Hippocampal Glutamate Receptors in a Rat Model 
NUTRIENTS
MDPI
2022
Articolo
Open Access
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Single and Repeated Exposure to Cannabidiol Differently Modulate BDNF Expression and Signaling in the Cortico-Striatal Brain Network 
BIOMEDICINES
MDPI
2022
Articolo
Open Access
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The antiviral and immunomodulatory activities of propolis: An update and future perspectives for respiratory diseases 
MEDICINAL RESEARCH REVIEWS
WILEY BLACKWELL PUBLISHING
2022
Articolo
Open Access
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Transient rapamycin treatment during developmental stage extends lifespan in Mus musculus and Drosophila melanogaster 
EMBO REPORTS
WILEY BLACKWELL PUBLISHING
2022
Articolo
Open Access
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Unveiling the Ability of Witch Hazel (Hamamelis virginiana L.) Bark Extract to Impair Keratinocyte Inflammatory Cascade Typical of Atopic Eczema 
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
MDPI
2022
Articolo
Open Access
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Vitamin D Repletion and AA/EPA Intake in Children with Type 1 Diabetes: Influences on Metabolic Status 
NUTRIENTS
MDPI
2022
Articolo
Open Access
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Alterations of gut microbiota composition in post-finasteride patients: a pilot study 
JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION
SPRINGER
2021
Articolo
Open Access
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Anti-Müllerian Hormone, Growth Hormone, and Insulin-Like Growth Factor 1 Modulate the Migratory and Secretory Patterns of GnRH Neurons 
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
MDPI
2021
Articolo
Open Access
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Apoptosis-mediated anticancer activity in prostate cancer cells of a chestnut honey (Castanea sativa L.) quinoline-pyrrolidine gamma-lactam alkaloid 
AMINO ACIDS
SPRINGER
2021
Articolo
Open Access
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Dissecting the Hormonal Signaling Landscape in Castration-Resistant Prostate Cancer 
CELLS
MDPI
2021
Articolo
Open Access
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Exploring the impact of the microbiome on neuroactive steroid levels in germ-free animals 
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
MDPI
2021
Articolo
Open Access
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Hemolymph proteins: An overview across marine arthropods and molluscs 
JOURNAL OF PROTEOMICS
ELSEVIER
2021
Articolo
Open Access
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In vitro 3D cultures to model the tumor microenvironment 
CANCERS
MDPI
2021
Articolo
Open Access
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Iron metabolism in pancreatic beta-cell function and dysfunction 
CELLS
MDPI
2021
Articolo
Open Access
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Oligodendrocyte Dysfunction in Amyotrophic Lateral Sclerosis: Mechanisms and Therapeutic Perspectives 
CELLS
MDPI
2021
Articolo
Open Access
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PCSK9 deficiency rewires heart metabolism and drives heart failure with preserved ejection fraction 
EUROPEAN HEART JOURNAL
OXFORD UNIVERSITY PRESS
2021
Articolo
Open Access
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Structural investigation and molecular modeling studies of strobilurin-based fungicides active against the rice blast pathogen Pyricularia oryzae 
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
MDPI
2021
Articolo
Open Access
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Three-Dimensional Proteome-Wide Scale Screening for the 5-Alpha Reductase Inhibitor Finasteride: Identification of a Novel Off-Target 
JOURNAL OF MEDICINAL CHEMISTRY
AMERICAN CHEMICAL SOCIETY (ACS)
2021
Articolo
Open Access
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Activity-Based Anorexia Dynamically Dysregulates the Glutamatergic Synapse in the Nucleus Accumbens of Female Adolescent Rats 
NUTRIENTS
MDPI
2020
Articolo
Open Access
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Born to Protect: Leveraging BDNF Against Cognitive Deficit in Alzheimer's Disease 
CNS DRUGS
ADIS INTERNATIONAL
2020
Articolo
Partially Open Access
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Development of an adverse outcome pathway for cranio-facial malformations: A contribution from in silico simulations and in vitro data 
FOOD AND CHEMICAL TOXICOLOGY
ELSEVIER
2020
Articolo
Open Access
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Development of the first in vivo GPR17 ligand through an iterative drug discovery pipeline: A novel disease-modifying strategy for multiple sclerosis 
PLOS ONE
PUBLIC LIBRARY OF SCIENCE
2020
Articolo
Open Access
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Grapes and their derivatives in modulation of cognitive decline: a critical review of epidemiological and randomized-controlled trials in humans 
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
TAYLOR & FRANCIS GROUP
2020
Articolo
Open Access
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Lipidomic analysis of cancer cells cultivated at acidic pH reveals phospholipid fatty acids remodelling associated with transcriptional reprogramming 
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
TAYLOR & FRANCIS
2020
Articolo
Open Access
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Low-protein/high-carbohydrate diet induces AMPK-dependent canonical and non-canonical thermogenesis in subcutaneous adipose tissue 
REDOX BIOLOGY
ELSEVIER
2020
Articolo
Open Access
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Mitochondrial functional and structural impairment is involved in the antitumor activity of δ-tocotrienol in prostate cancer cells 
FREE RADICAL BIOLOGY & MEDICINE
ELSEVIER
2020
Articolo
Reserved Access
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The Absence of Serotonin in the Brain Alters Acute Stress Responsiveness by Interfering With the Genomic Function of the Glucocorticoid Receptors 
FRONTIERS IN CELLULAR NEUROSCIENCE
FRONTIERS RESEARCH FOUNDATION
2020
Articolo
Open Access
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The metaplastic effects of ketamine on sucrose renewal and contextual memory reconsolidation in rats 
BEHAVIOURAL BRAIN RESEARCH
ELSEVIER
2020
Articolo
Partially Open Access
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Three-Dimensional Cell Cultures as an In Vitro Tool for Prostate Cancer Modeling and Drug Discovery 
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
MDPI
2020
Articolo
Open Access
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Cellular and molecular biology of cancer stem cells in melanoma : possible therapeutic implications 
SEMINARS IN CANCER BIOLOGY
ELSEVIER
2019
Articolo
Partially Open Access
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SLC6A14, a Pivotal Actor on Cancer Stage: When Function Meets Structure 
SLAS DISCOVERY
SAGE PUBLICATIONS
2019
Articolo
Open Access
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Set-up and validation of a high throughput screening method for human monoacylglycerol lipase (MAGL) based on a new red fluorescent probe 
MOLECULES
MDPI
2019
Articolo
Open Access
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Effects of Vegetable Proteins on Hypercholesterolemia and Gut Microbiota Modulation 
NUTRIENTS
MDPI
2018
Articolo
Open Access
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