Personal information

Family name, First name: Mollica, Luca
ORCID: 0000-0001-5403-9507
Date of birth: 10/10/1977


Current positions

12/2020 – present
Fixed-term Research Fellow B (CHIM/02), Department of Medical Biotechnologies and Translational Medicine, University of Milan, Italy

10/2018 - present
Assistant Professor of General Chemistry, Bachelor in Medical Biotechnologies, University of Milan, Italy.

04/2018 – present
Member of the organizing committee of the Master in Bioinformatics and Functional Genomics, University of Milan, Italy.


Working and professional experience

04/2018 – 11/2020
Postdoctoral Fellow B, Integrative Biology Unit, Istituto Nazionale Genetica Molecolare (INGM) / Department of Medical Biotechnologies and Translational Medicine, University of Milan, Italy.

01/2014 - 01/2018
Senior Postdoctoral Fellow, Compunet / Istituto Italyno di Tecnologia, Genova, Italy

05/2015 - 01/2018
Scientific consultant, BiKi Technologies s.r.l. , Genova, Italy
03/2010 - 01/2014
Postdoctoral Fellow (Ingenieur de Recherche/Chercheur), Protein Dynamics and Flexibility by NMR Group, Institut de Biologie Structurale (IBS), Grenoble, France.

11/2008 - 02/2010
Postdoctoral Fellow, Biomolecular NMR Laboratory, DIBIT/IRCCS Ospedale San Raffaele, Milan, Italy
09/2005 - 01/2006
Visiting scientist, International Business Machine (IBM), Zurich Research Laboratory, Rueschlikon, Switzerland

05/2003 - 11/2008
Predoctoral Fellow, Biomolecular NMR Laboratory, DIBIT/IRCCS Ospedale San Raffaele, Milan, Italy

07/2002 – 05/2003
Predoctoral fellow (civil servant), Protein Chemistry and Biochemistry Laboratory, Istituto di ricerche Farmacologiche “Mario Negri” (IRFMN), Milan, Italy.



Teaching experience

2019-2020
Lecturer for the “Data handling in biomedical sciences” for the II level Master in Medical Biotechnology and Molecular Medicine, Università degli Studi di Milano.

2018-2019/2019-2020
Invited lecturer for the “Chimica e Chimica computazionale” course (Prof.Massimo Mella) for the II level Master in Chemistry and Industrial Chemistry, Università degli Studi dell’Insubria, Como, Italy.

2018-2019/2019-2020/2020-2021
Assistant professor of General Chemistry for the I level Master in Medical Biotechnologies, Università degli Studi di Milano, Italy.

2018-2019/2019-2020
Laboratory tutor for the “Molecular biology applied to biotechnology” course (Prof. Massimiliano Pagani) for the II level Master in Medical Biotechnology and Molecular Medicine, Università degli Studi di Milano, Italy.

2018-2019/2019-2020/2020-2021
Responsible of the organization of the Master in Bioinformatics and Functional Genomics, Università degli Studi di Milano / INGM (Coordinator: Prof. Massimiliano Pagani), Italy.

2018-2019/2020-2021
Lectrurer of the “Structural Biology” module of the Master in Bioinformatics and Functional Genomics, Università degli Studi di Milano / INGM (Coordinator: prof.Massimiliano Pagani), Italy.

2017-2018
Tutor for the “Cells molecules and genes” course, International Medical School, Università degli Studi di Milano, Italy.

2010
Lecturer of the “Scuola Nazionale di NMR”, 09.2010, Turin, Italy.


Professional skills

Computational Physical Chemistry: classical molecular dynamics, classical Monte Carlo molecular simulations, molecular docking, DFT-based calculations of molecular properties.

Experimental Biophysical Chemistry: multidimensional NMR spectroscopy of proteins and nucleic acids, circular dichroism, fluorescence spectroscopy.

Computational Biology and Bioinformatics: bulk RNA “de novo” sequencing, statistical inference and network analysis of gene expression.


Education and training

11/2008
PhD in Molecular and Cell Biology (broad area: Biophysical Chemistry), “Vita Salute – S.Raffaele”, Milan, and Open University of London, UK, International PhD Program

03/2002
Master Degree in Chemistry (broad area: Physical Chemistry), University of Milan, Italy


Languages

Italyn: mother tongue.
English: fluent in writing and reading.
French: fluent in writing and reading.


Further information

Scientific publications and bibliometric indexes

39 publications on peer reviewed journals
Last 10 years publications: 30
First author publications: 9
Corresponding author publications: 5

H index: 20
10 years H index: 15

Total number of citations:1945
Last 5 years citations: 963


National scientific habilitation (ASN)

Associate professor habilitation 2017-2026, SSD 03/A2 (Models and Methodologies for Chemical Sciences)
Associate professor habilitation 2018-2027 SSD 05/E1 (General Biochemistry)
Associate professor habilitation 2018-2027 SSD 02/D1 (Applied Physics)


Editorial activities

Editor of the topic "Protein dynamics and molecular recognition at the crossroad between experiments and theory", Frontiers in Molecular Biosciences.
Reviewer for Current Computer-Aided Drug Design, PLOS One, Scientific Reports, Journal of Chemical Theory and Computation.


Awards and Fellowships

Marie Curie Fellowship, 2011-2013
Bruker fellowship, XI Chianti Workshop on Magnetic Resonance, 2007, Vallombrosa, Italy.
EMBO fellowship, NMR Practical Course, 2005, Basel, CH.


Scientific congresses presentations

05.09.2016 - 07.09.2016
15th National Congress on Magnetic Resonance (GIDRM), Modena, Italy
"Protein dynamics and NMR observables: new approaches from enhanced sampling methods"(invited speaker)

16.10.2015
GIDRM - NMR Day on drug discovery and delivery: new approaches, Genova, Italy (organizer)

22.09.2015 - 25.09.2015
CECAM Workshop: Computational Advances in Drug Discovery, Losanna, CH.
"Kinetics of protein-ligand unbinding via smoothed potential molecular dynamics simulations" (poster)

10.06.2014 - 12.06.2014
CECAM Workshop: Binding free energy and kinetics: computation meets experiments, Genova, Italy.
"In Silico Prediction of Protein Unbinding Kinetics Using Smoothed Potentials"(invited speaker)

21.11.2013
Natta's Seeds Grow, Milano, Italy
"Atomic-Resolution Structural Dynamics in Crystalline Proteins from NMR and Molecular Simulation".
Milano, Italy (poster)

24.09.2012 - 26.09.2012
CECAM Workshop: Exploring Protein Interactions through Theory and Experiment, Losanna, CH.
"Multi-timescale dynamics of crystalline proteins investigated using molecular dynamics simulations and high-resolution solid-state NMR spectroscopy" (invited speaker)

17.06.2012 - 22.06.2012
12th Chianti.INSTRUCT Workshop on BioNMR, Electron and Nuclear Relaxation for - Structural Biology Montecatini Terme, Italy.
"Atomic-Resolution Structural Dynamics in Crystalline Proteins from NMR and Molecular Simulation" (poster)

14.12.2008 - 18.12.2008
NMR to lay the bricks for molecular systems biology, Montecatini Terme, Italy
"The anti-inflammatory effect of Glychyrryzin and its interactions with extracellular HMGB1 revealed by NMR and MD"(poster)

03.06.2007 - 08.06.2007
11th Chianti Workshop on Magnetic Resonance, Vallombrosa, Italy
"Glycyrrhizin Binds to High Mobility Group Box 1 Protein (HMGB1) and Inhibits its Cytokine Activities"(poster)