Preparation of radionuclides and their measurement by high resolution gamma-spectrometry, beta-spectrometry and high resolution alpha-spectrometry

The use of High Specific Activity Radionuclides HSARNs, obtained by either proton, deuteron or alpha cyclotron irradiation, followed by selective radiochemical separation from the irradiated target in No Carrier Added (NCA) form, is a powerful analytical tool. The main applications of these radionuclides are to medical dignosis and therapy in addition to toxicological, environmental and industrial studies. These NCA radionuclides and their Specific Activity (AS) can reach values close to the theoretical “carrier-free” one AS(CF). The “real” AS(NCA) must by measured by either analytical or/and radioanalytical techniques. The “accurate” knowledge of behavior of cross-sections of each reaction, as a function of beam energy (excitation functions) is mandatory. The minimization of Isotopic Dilution Factor is achieved also. Some examples of production and radioanalytical quality control methods for HSARNs are presented.