Localized erosive pustular dermatosis of the scalp at the site of a cochlear implant: successful treatment with topical tacrolimus
Articolo
Data di Pubblicazione:
2009
Citazione:
Localized erosive pustular dermatosis of the scalp at the site of a cochlear implant: successful treatment with topical tacrolimus / A.V. Marzano, M. Ghislanzoni, A. Zaghis, D. Spinelli, C. Crosti. - In: CLINICAL AND EXPERIMENTAL DERMATOLOGY. - ISSN 0307-6938. - 34:5(2009 Jul), pp. e157-e159.
Abstract:
Erosive pustular dermatosis of the scalp EPDS) is a rare form of nonmicrobial
pustulosis mainly occurring in elderly patients with long-term sun damage to the
skin. Clinically, it is characterized by pustular lesions that progressively
merge into erosive and crusted areas over the scalp. The histology of EPDS is
nonspecific, and its pathophysiology remains undetermined, with various types of local trauma possibly acting as the triggering factor. We describe a 24-year-old woman who developed EPDS after cochlear implant surgery for profound sensorineural hearing loss. We speculate that either the cutaneous surgery during cochlear implantation or the skin inflammation that commonly occurs near the magnet might have triggered the disorder. It is of note that the patient's skin lesions healed completely after treatment with topical tacrolimus, a relatively novel immunosuppressive molecule. Thus, topical tacrolimus may be indicated as a therapeutic alternative to the widely used steroids for this disease, mainly to
avoid steroid-related cutaneous atrophy.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Young Adult ; Cochlear Implantation ; Scalp ; Humans ; Biopsy ; Tacrolimus ; Scalp Dermatoses ; Immunosuppressive Agents ; Female
Elenco autori:
A.V. Marzano, M. Ghislanzoni, A. Zaghis, D. Spinelli, C. Crosti
Link alla scheda completa: