Extremely Preterm Infant Admissions Within the SafeBoosC-III Consortium During the COVID-19 Lockdown
Articolo
Data di Pubblicazione:
2021
Citazione:
Extremely Preterm Infant Admissions Within the SafeBoosC-III Consortium During the COVID-19 Lockdown / M.I. Rasmussen, M.L. Hansen, G. Pichler, E. Dempsey, A. Pellicer, A. EL-Khuffash, S. A, S. Piris-Borregas, M. Alsina, M. Cetinkaya, L. Chalak, H. Ozkan, M. Baserga, J. Sirc, H. Fuchs, E. Ergenekon, L. Arruza, A. Mathur, M. Stocker, O. Otero Vaccarello, T. Szczapa, K. Sarafidis, B. Krolak-Olejnik, A. Memisoglu, H. Reigstad, E. Rafinska-Wazny, E. Hatzidaki, Z. Peng, D. Gkentzi, R. Viellevoye, J. De Buyst, E. Mastretta, P. Wang, G.H. Hahn, L. Bender, L. Cornette, J. Tkaczyk, R. del Rio, M. Fumagalli, E. Papathoma, M. Wilinska, G. Naulaers, I. Sadowska-Krawczenko, C. Lecart, M.L. Couce, S. Fredly, A.M. Heuchan, T. Karen, G. Greisen. - In: FRONTIERS IN PEDIATRICS. - ISSN 2296-2360. - 9(2021), pp. 647880.1-647880.8. [10.3389/fped.2021.647880]
Abstract:
Objective: To evaluate if the number of admitted extremely preterm (EP) infants (born before 28 weeks of gestational age) differed in the neonatal intensive care units (NICUs) of the SafeBoosC-III consortium during the global lockdown when compared to the corresponding time period in 2019. Design: This is a retrospective, observational study. Forty-six out of 79 NICUs (58%) from 17 countries participated. Principal investigators were asked to report the following information: (1) Total number of EP infant admissions to their NICU in the 3 months where the lockdown restrictions were most rigorous during the first phase of the COVID-19 pandemic, (2) Similar EP infant admissions in the corresponding 3 months of 2019, (3) the level of local restrictions during the lockdown period, and (4) the local impact of the COVID-19 lockdown on the everyday life of a pregnant woman. Results: The number of EP infant admissions during the first wave of the COVID-19 pandemic was 428 compared to 457 in the corresponding 3 months in 2019 (−6.6%, 95% CI −18.2 to +7.1%, p = 0.33). There were no statistically significant differences within individual geographic regions and no significant association between the level of lockdown restrictions and difference in the number of EP infant admissions. A post-hoc analysis based on data from the 46 NICUs found a decrease of 10.3%in the total number of NICU admissions (n = 7,499 in 2020 vs. n = 8,362 in 2019). Conclusion: This ad hoc study did not confirm previous reports of a major reduction in the number of extremely pretermbirths during the first phase of the COVID-19 pandemic. Clinical Trial Registration: ClinicalTrial.gov, identifier: NCT04527601 (registered August 26, 2020), https://clinicaltrials.gov/ct2/show/NCT04527601.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
COVID-19; extremely preterm; neonatal intensive care unit admission; observational study; pandemic; randomized clinical trial
Elenco autori:
M.I. Rasmussen, M.L. Hansen, G. Pichler, E. Dempsey, A. Pellicer, A. EL-Khuffash, S. A, S. Piris-Borregas, M. Alsina, M. Cetinkaya, L. Chalak, H. Ozkan, M. Baserga, J. Sirc, H. Fuchs, E. Ergenekon, L. Arruza, A. Mathur, M. Stocker, O. Otero Vaccarello, T. Szczapa, K. Sarafidis, B. Krolak-Olejnik, A. Memisoglu, H. Reigstad, E. Rafinska-Wazny, E. Hatzidaki, Z. Peng, D. Gkentzi, R. Viellevoye, J. De Buyst, E. Mastretta, P. Wang, G.H. Hahn, L. Bender, L. Cornette, J. Tkaczyk, R. del Rio, M. Fumagalli, E. Papathoma, M. Wilinska, G. Naulaers, I. Sadowska-Krawczenko, C. Lecart, M.L. Couce, S. Fredly, A.M. Heuchan, T. Karen, G. Greisen
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