Data di Pubblicazione:
2020
Citazione:
Gold nanoparticle-based platforms for vaccine development / R.M. Ferrando, L. Lay, L. Polito. - In: DRUG DISCOVERY TODAY: TECHNOLOGIES. - ISSN 1740-6749. - 38:(2020 Dec), pp. 57-67. [10.1016/j.ddtec.2021.02.001]
Abstract:
Since their discovery, therapeutic or prophylactic vaccines
represent a promising option to prevent or cure
infections and other pathologies, such as cancer or
autoimmune disorders. More recently, among a number
of nanomaterials, gold nanoparticles (AuNPs) have
emerged as novel tools for vaccine developments,
thanks to their inherent ability to tune and upregulate
immune response. Moreover, owing to their features,
AuNPs can exert optimal actions both as delivery
systems and as adjuvants. Notwithstanding the potential
huge impact in vaccinology, some challenges remain
before AuNPs in vaccine formulations can be
translated into the clinic. The current review provides
an updated overview of the most recent and effective
application of gold nanoparticles as efficient means to
develop a new generation of vaccine.
Tipologia IRIS:
01 - Articolo su periodico
Elenco autori:
R.M. Ferrando, L. Lay, L. Polito
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