Assessment of spatial organization in the atria during paroxysmal atrial fibrillation and adrenergic stimulation
Articolo
Data di Pubblicazione:
2006
Citazione:
Assessment of spatial organization in the atria during paroxysmal atrial fibrillation and adrenergic stimulation / V.D.A. CORINO, M. MANTICA, F. LOMBARDI, L.T. MAINARDI. - In: BIOMEDIZINISCHE TECHNIK. - ISSN 0013-5585. - 51:4(2006), pp. 260-263.
Abstract:
Non-linear parameters were computed to assess the extent of spatial organization in the atria in terms of coupling/synchronization between electrograms recorded in different atrial sites. Recordings of 9 patients suffering from paroxysmal atrial fibrillation were tested during four clinical experimental conditions: sinus rhythm and atrial fibrillation, both before and after isoproterenol infusion, a drug mimicking adrenergic activation. Two non-linear metrics were investigated: an index of non-linear association (NLA) and a synchronization (S) index based on the cross-conditional entropy. Results evidence the presence of reduced coupling after drug infusion in both sinus rhythm and atrial fibrillation. Moreover, passing from the NLA to the S index, the capability of the parameter to capture the subtle changes due to isoproterenol administration increased.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
adrenergic stimulation; atrial fibrillation; endocardial recordings; non-linear analysis; synchronization
Elenco autori:
V.D.A. CORINO, M. MANTICA, F. LOMBARDI, L.T. MAINARDI
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