Data di Pubblicazione:
2020
Citazione:
Frozen IVF Cycles to Circumvent the Hormonal Storm on Endometrium / P. Vigano, A. Alteri, A. Busnelli, V.S. Vanni, E. Somigliana. - In: TRENDS IN ENDOCRINOLOGY AND METABOLISM. - ISSN 1043-2760. - 31:4(2020 Apr), pp. 296-307.
Abstract:
Controlled ovarian hyperstimulation (COH) determines an anticipation of endometrial maturation and a premature occurrence of the implantation window, as shown by histological, histochemical, and molecular studies and indirectly by clinical trials. There is growing agreement that in patients hyper-responding to COH and in those undergoing transfer at the blastocyst stage, deferring the transfer in a subsequent frozen cycle could increase pregnancy outcomes. For blastocysts, implantation after a fresh transfer may be limited as the implantation window is already closed while, in hyper-responders to COH, the anticipation magnitude could be more marked thus hampering implantation also for cleavage-stage embryos. Research should focus in depth on pregnancy outcomes and on the most suitable modality to prepare the endometrium for frozen transfers.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
controlled ovarian hyperstimulation; endometrium; frozen cycles; IVF
Elenco autori:
P. Vigano, A. Alteri, A. Busnelli, V.S. Vanni, E. Somigliana
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