beta-Lactam Bioconjugates Bearing Luminescent Platinum(II) Tags: Synthesis and Photophysical Characterization
Articolo
Data di Pubblicazione:
2014
Citazione:
beta-Lactam Bioconjugates Bearing Luminescent Platinum(II) Tags: Synthesis and Photophysical Characterization / R. Soldati, A. Alipri, M. Mauro, L. De Cola, D. Giacomini. - In: EUROPEAN JOURNAL OF ORGANIC CHEMISTRY. - ISSN 1434-193X. - 2014:32(2014), pp. 7113-7121. [10.1002/ejoc.201402740]
Abstract:
Two novel neutral complexes based on platinum metal ions, a tridentate ligand, and a pyridine bearing a beta-lactam unit have been synthesized and their photophysical properties investigated. The complexes show interesting emission properties that, in the solid state, are dominated by the formation of aggregates due to the square-planar geometry of the Pt-II species. Importantly, the formation of closed-shell metal center dot center dot center dot metal interactions in such aggregates leads to new excited states that conveniently allow excitation in the visible region. The combination of the biologically active azetidinone agent and the intense and long-lived emission are of particular interest for developing efficient multifunctional biomedical systems.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Bioprobes; Lactams; Theranostic agents; Bioimaging; Platinum; Luminescence
Elenco autori:
R. Soldati, A. Alipri, M. Mauro, L. De Cola, D. Giacomini
Link alla scheda completa: