Assessment of the coupling between RTapex and RR interval as an index of temporal dispersion of ventricular repolarization
Articolo
Data di Pubblicazione:
1998
Citazione:
Assessment of the coupling between RTapex and RR interval as an index of temporal dispersion of ventricular repolarization / F. Lombardi, A. Colombo, A. Porta, G. Baselli, S. Cerutti, C. Fiorentini. - In: PACING AND CLINICAL ELECTROPHYSIOLOGY. - ISSN 0147-8389. - 21:11 Pt 2(1998), pp. 2396-2400.
Abstract:
To evaluate the dynamic characteristics of the relationship between the RT and RR intervals we analyzed the RR/RTapex variability interaction with a dynamic parametric model whose parameters can be directly estimated from the beat-to-beat series RR and RTapex intervals. The model is designed to separate the fraction of RTapex variability driven by RR changes from that independent of RR variations and to quantify the gain and phase of the relationship between RR and RTapex intervals. The percentage of RTapex variability driven by RR variability was significantly greater in young normal subjects in comparison with postmyocardial infarction patients as well as with age-matched control subjects. This new approach based on the quantification of the RTapex variability dependent and independent of beat-to-beat RR interval changes could be used to quantify the degree of uncoupling between the two signals thus providing a new and noninvasive index of temporal dispersion of ventricular repolarization.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
QT dispersion; QT interval; Spectral analysis; Ventricular repolarization
Elenco autori:
F. Lombardi, A. Colombo, A. Porta, G. Baselli, S. Cerutti, C. Fiorentini
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