Data di Pubblicazione:
2020
Citazione:
Cutaneous metastases of prostatic adenocarcinoma in two dogs / F.M. Di Maria, M. Annoni, P. Roccabianca, E. Antoniazzi, W. Bertazzolo. - In: VETERINARY CLINICAL PATHOLOGY. - ISSN 0275-6382. - (2020 Aug 31). [Epub ahead of print] [10.1111/vcp.12888]
Abstract:
Canine prostatic adenocarcinoma is an aggressive malignancy characterized by rapid
growth, local invasiveness, and early metastatic spread. Metastases of prostatic cancer
are generally diffuse at the time of diagnosis due to hematogenous or lymphatic
spread and by direct exfoliation of neoplastic cells into the peritoneal cavity. Here
we describe two dogs with prostatic adenocarcinoma and skin metastases. The first
was a 12-year-old intact male German Shepherd dog that was presented with a history
of chronic prostatic disease and multiple skin nodules that recently appeared
on the ventral abdomen. The second was an 8-year-old intact male mixed breed dog
that was referred for a neurologic examination because of a 1-month history of back
pain and kyphosis of undefined origin. Cutaneous cytology of the first case was suggestive
of carcinoma, and at necropsy, prostatic adenocarcinoma with metastases to
the skin, spleen, liver, pancreas, kidneys, and lungs were found. In the second case,
a computed tomographic examination revealed a prostatic neoplasm with inguinal,
subcutaneous, and cutaneous nodular metastases. Cytology and histopathology
were suggestive of primary prostatic adenocarcinoma with cutaneous and subcutaneous
metastases. To the authors' knowledge, these are the first reported cases of
prostatic adenocarcinoma skin metastases in dogs with cytologic descriptions.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
canine; metastatic cancer; prostate; skin
Elenco autori:
F.M. Di Maria, M. Annoni, P. Roccabianca, E. Antoniazzi, W. Bertazzolo
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