Studio degli ormoni iposifo-gonadici ad insorgenza post-menopausale in alcuni casi di asma bronchiale
Articolo
Data di Pubblicazione:
1986
Citazione:
Studio degli ormoni iposifo-gonadici ad insorgenza post-menopausale in alcuni casi di asma bronchiale / F. Farina, S. Colombi, R. Cantone, M. Pastore, S. Centanni, M. Galimberti. - In: MINERVA MEDICA. - ISSN 0026-4806. - 77:7-8(1986), pp. 243-247.
Abstract:
A study was conducted into the hormone profile of women with no previous history of allergy who developed bronchial asthma after menopause in order to discover any differences between these and patients of a similar age with allergic bronchial asthma. The serum levels of the following hypophyseal and gonadal hormones were therefore analysed: luteinizing hormone (LH), follicle stimulating hormone (FSH), prolactin (PRL), 17 oestradiol (17BE2) in both groups of patients and in a control group of healthy post-menopausal volunteers. The results showed lower FSH and LH and higher 17BE2 levels in the patients with bronchial asthma but no clinical history of allergy than in either the patients with allergic asthma or the healthy volunteers. When the hormone picture in some of the group 1 patients normalised, the clinical symptoms disappeared. One possible explanation is the following: excess oestrogen in the ''non-allergy'' patients might have caused an imbalance in the PgF/PgE ratio which is thought to contribute to the regulation of bronchomotor tone. The same phenomena might also have accelerated the release of arachidonic acid and its metabolites.
Tipologia IRIS:
01 - Articolo su periodico
Elenco autori:
F. Farina, S. Colombi, R. Cantone, M. Pastore, S. Centanni, M. Galimberti
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