Altered corticospinal microstructure and motor cortex excitability in gliomas : an advanced tractography and transcranial magnetic stimulation study
Articolo
Data di Pubblicazione:
2021
Citazione:
Altered corticospinal microstructure and motor cortex excitability in gliomas : an advanced tractography and transcranial magnetic stimulation study / A.S. Mirchandani, A. Beyh, J.P. Lavrador, H. Howells, F. Dell'Acqua, F. Vergani. - In: JOURNAL OF NEUROSURGERY. - ISSN 0022-3085. - 134:5(2021 May), pp. 1368-1376. [10.3171/2020.2.JNS192994]
Abstract:
This prospective case-control study was conducted to examine whether spherical deconvolution (SD) can unveil microstructural abnormalities in the corticospinal tract (CST) caused by IDH-mutant gliomas. To determine the significance of abnormal microstructure, the authors investigated the correlation between diffusion parameters and neurophysiological data collected with navigated transcranial magnetic stimulation (nTMS).
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
AD = axial diffusivity; CST = corticospinal tract; DTI = diffusion tensor imaging; FA = fractional anisotropy; HMOA = hindrance modulated orientational anisotropy; MD = mean diffusivity; MEP = motor evoked potential; MRC = Medical Research Council; RD = radial diffusivity; ROI = region of interest; SD = spherical deconvolution; corticospinal tract; fODF = fiber orientation distribution function; low-grade gliomas; nTMS = navigated transcranial magnetic stimulation; oncology; pathological excitability; rMT = resting motor threshold; resting motor threshold; spherical deconvolution; tractography; transcranial magnetic stimulation
Elenco autori:
A.S. Mirchandani, A. Beyh, J.P. Lavrador, H. Howells, F. Dell'Acqua, F. Vergani
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