Diagnostic performance of non-invasive imaging for stable coronary artery disease : ameta-analysis
Articolo
Data di Pubblicazione:
2020
Citazione:
Diagnostic performance of non-invasive imaging for stable coronary artery disease : ameta-analysis / G. Pontone, A.I. Guaricci, S.C. Palmer, D. Andreini, M. Verdecchia, L. Fusini, V. Lorenzoni, M. Guglielmo, G. Muscogiuri, A. Baggiano, M.G. Rabbat, F. Cademartiri, G.F. Strippoli. - In: INTERNATIONAL JOURNAL OF CARDIOLOGY. - ISSN 0167-5273. - 300(2020 Feb), pp. 276-281.
Abstract:
Background: To determine diagnostic performance of non-invasive tests using invasive fractional flow reserve (FFR) as reference standard for coronary artery disease (CAD). Methods: Medline, Embase, and citations of articles, guidelines, and reviews for studies were used to compare non-invasive tests with invasive FFR for suspected CAD published through March 2017. Results: Seventy-seven studies met inclusion criteria. The diagnostic test with the highest sensitivity to detect a functionally significant coronary lesion was coronary computed tomography (CT) angiography [88%(85%–90%)], followed by FFR derived from coronary CT angiography (FFRCT) [85%(81%–88%)], positron emission tomography (PET) [85%(82%–88%)], stress cardiac magnetic resonance (stress CMR) [81%(79%–84%)], stress myocardial CT perfusion combined with coronary CT angiography [79%(74%–83%)], stress myocardial CT perfusion [77%(73%–80%)], stress echocardiography (Echo) [72%(64%–78%)] and stress single-photon emission computed tomography (SPECT) [64%(60%–68%)]. Specificity to rule out CAD was highest for stress myocardial CT perfusion added to coronary CT angiography [91%(88%–93%)], stress CMR [91%(90%–93%)], and PET [87%(86%–89%)]. Conclusion: A negative coronary CT angiography has a higher test performance than other index tests to exclude clinically-important CAD. A positive stress myocardial CT perfusion added to coronary CT angiography, stress cardiac MR, and PET have a higher test performance to identify patients requiring invasive coronary artery evaluation.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Coronary artery disease; Diagnostic pathway; Fractional flow reserve; Meta-analysis; Non-invasive test
Elenco autori:
G. Pontone, A.I. Guaricci, S.C. Palmer, D. Andreini, M. Verdecchia, L. Fusini, V. Lorenzoni, M. Guglielmo, G. Muscogiuri, A. Baggiano, M.G. Rabbat, F. Cademartiri, G.F. Strippoli
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