Correlation between ganglioside distribution and histological grading of human astrocytomas
Articolo
Data di Pubblicazione:
1985
Citazione:
Correlation between ganglioside distribution and histological grading of human astrocytomas / B. Berra, S.M. Gaini, L. Riboni. - In: INTERNATIONAL JOURNAL OF CANCER. - ISSN 0020-7136. - 36:3(1985), pp. 363-366. [10.1002/ijc.1985.36.3.363]
Abstract:
Changes in membrane lipid content and composition have been repeatedly detected in experimentally induced as well as spontaneous tumors. Previous data on ganglioside analysis in human astrocytomas suggested a possible correlation between their content and pattern and the histological grading of these tumors. In our study we could definitely prove this correlation: in fact the level of malignancy, passing from grade I to grade IV, is associated with a statistically significant increase of a ganglioside identified as ganglioside GD3. Another important modification in the ganglioside pattern of human astrocytomas is the decrease in polysialylated species with increasing level of malignancy.
Tipologia IRIS:
01 - Articolo su periodico
Elenco autori:
B. Berra, S.M. Gaini, L. Riboni
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