Quadruplex knots as network nodes: nano-partitioning of guanosine derivates in supramolecular hydrogels
Articolo
Data di Pubblicazione:
2019
Citazione:
Quadruplex knots as network nodes: nano-partitioning of guanosine derivates in supramolecular hydrogels / G. Nava, F. Carducci, R. Itri, J.S. Yoneda, T. Bellini, P. Mariani. - In: SOFT MATTER. - ISSN 1744-6848. - 15:11(2019 Mar 21), pp. 2315-2318. [10.1039/C8SM02616E]
Abstract:
Aqueous solutions of guanosine-5′-monophosphates (GMP)-known to form G-quadruplexes and liquid crystal phases-can be induced to turn into high water content gels by the addition of guanosine (Gua). By a combination of Light Scattering (LS) and AFM we show that Gua/GMP hydrogels are microscopically heterogeneous, formed by Gua-rich disordered microcoils of intertwined filaments (“knots”) connected by GMP-rich long linear threads. The different thermal stability of knots and threads controls the gel transition.
Tipologia IRIS:
01 - Articolo su periodico
Elenco autori:
G. Nava, F. Carducci, R. Itri, J.S. Yoneda, T. Bellini, P. Mariani
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