Data di Pubblicazione:
2008
Citazione:
A compact and disposable transdermal drug delivery system / M. Matteucci, M. Casella, M. Bedoni, E. Donetti, M. Fanetti, F. De Angelis, F. Gramatica, E. Di Fabrizio. - In: MICROELECTRONIC ENGINEERING. - ISSN 0167-9317. - 85:5-6(2008), pp. 1066-1073. [10.1016/j.mee.2007.12.067]
Abstract:
This work presents a portable transdermal drug delivery system that combines a magnetically actuated micro gear pump with a microneedle array. Micropart fabrication is performed through DXRL and LIGA techniques. The manufacturing process of both micropump and microneedle array are described together with wear issues. Results show that the assembled device can deliver rates that go from 0.1 to 1.2 ml/min at gear speed ranging from 1000 to 8500 rpm. First skin piercing experiments are also described.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Deep X-ray lithography; LIGA; Soft lithography; Transdermal drug delivery
Elenco autori:
M. Matteucci, M. Casella, M. Bedoni, E. Donetti, M. Fanetti, F. De Angelis, F. Gramatica, E. Di Fabrizio
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