Determination of polycyclic aromatic hydrocarbons in lipstick by gas-chromatography coupled to mass spectrometry: A case history
Articolo
Data di Pubblicazione:
2019
Citazione:
Determination of polycyclic aromatic hydrocarbons in lipstick by gas-chromatography coupled to mass spectrometry: A case history / G. Roda, S. Arnoldi, E. Casagni, M. Dei Cas, L. Silva, M. Carini. - In: JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS. - ISSN 0731-7085. - 165:(2019), pp. 386-392. [10.1016/j.jpba.2018.12.029]
Abstract:
A suitable extraction protocol based on an liquid-liquid extraction with hexane/dimethyl sulfoxide and a GC/MS method were developed and validated to determine the concentration of six prohibited Polycyclic Aromatic Hydrocarbons (PAHs; benzo[a]pyrene; dibenz[a,h]anthracene; benz[a]anthracene; benzo[j]fluoranthene; benzo[k]fluoranthene; chrysene) in lipsticks commissioned by a cosmetic company to a manufacturer. The lipsticks were produced in four different colors. Analyses confirmed the presence of benz[a]anthracene and chrysene only in two colors in a concentration of 9.3–9.4 ng/g. The concentration of PAHs was 250 times lower than what is considered a toxic level on the basis of what reported in the litaraure and guidances for cosmetic ingredients; therefore we could assume that the risk for consumer health was negligeble.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Polycyclic aromatic hydrocarbons (PAHs); Cosmetic products; GC/MS; Liquid-liquid extraction
Elenco autori:
G. Roda, S. Arnoldi, E. Casagni, M. Dei Cas, L. Silva, M. Carini
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