Divergent Palladium- and Platinum-Catalyzed Intramolecular Hydroamination/Hydroarylation of O-Propargyl-2-aminophenols
Articolo
Data di Pubblicazione:
2018
Citazione:
Divergent Palladium- and Platinum-Catalyzed Intramolecular Hydroamination/Hydroarylation of O-Propargyl-2-aminophenols / M. Christodoulou, S. Giofrè, G. Broggini, A. Mazza, R. Sala, E.M. Beccalli. - In: EUROPEAN JOURNAL OF ORGANIC CHEMISTRY. - ISSN 1434-193X. - 2018:44(2018 Dec 02), pp. 6176-6184. [10.1002/ejoc.201801103]
Abstract:
A fruitful divergent cyclization of terminal alkynes arising from 2-aminophenols depending on the transition metal employed is reported. Under palladium- and platinum-catalysis, the total regioselective carbon–nitrogen or carbon–carbon bonds formation afforded 1,4-benzoxazines or benzopyrans, through different reaction pathways. The subsequent functionalization of the benzopyran scaffold paved the way for a new synthesis of the tricyclic pyrano[3,2-h]quinolines.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Divergent synthesis; Hydroamination; Hydroarylation; Palladium; Platinum; Physical and Theoretical Chemistry; Organic Chemistry
Elenco autori:
M. Christodoulou, S. Giofrè, G. Broggini, A. Mazza, R. Sala, E.M. Beccalli
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