Data di Pubblicazione:
2007
Citazione:
Immunopathology of Dirofilaria immitis Infection / F. Simon, L.H. Kramer, A. Roman, W. Blasini, R. Morchon, C. Marcos-Atxutegi, G. Grandi,
C. Genchi. - In: VETERINARY RESEARCH COMMUNICATIONS. - ISSN 0165-7380. - 31:2(2007), pp. 161-171.
Abstract:
Heartworm disease caused by Dirofilaria immitis affects canine and feline hosts,
with infections occasionally being reported in humans. Studies have shown that
both dirofilarial antigens and those derived from its bacterial endosymbiont
Wolbachia, interact with the host organism during canine, feline and human
infections and participate in the development of the pathology and in the
regulation of the host's immune response. Both innate and acquired immune
responses are observed and the development of the acquired response may depend
on the host and, or on its parasitological status. This review aims at
illustrating current research on the role of both D. immitis and Wolbachia, in
the immunology and immunopathology of dirofilariosis.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Canine; D. immitis; Feline and human infections; Inflammatory reactions; Pro-and antiinflammatory cytokine expression; TH1and TH2-type response; Wolbachia endosymbionts
Elenco autori:
F. Simon, L.H. Kramer, A. Roman, W. Blasini, R. Morchon, C. Marcos-Atxutegi, G. Grandi,
C. Genchi
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