Complete 1H and 13C assignments of (21R) and (21S) diastereomers of argatroban

Articolo
Data di Pubblicazione:
2008
Citazione:
Complete 1H and 13C assignments of (21R) and (21S) diastereomers of argatroban / D.R. Colombo, P. Ferraboschi, P. Grisenti, L. Legnani. - In: MAGNETIC RESONANCE IN CHEMISTRY. - ISSN 0749-1581. - 46:1(2008), pp. 99-102.
Abstract:
The complete 1H and 13C NMR assignments are reported for the antithrombotic (21R)- and (21S)-argatroban by 1D and 2D NMR experiments (HSQC, HMBC, NOESY and 1H--1H COSY). Some well-resolved signals could be used for an accurate measurement of the diastereomeric composition of argatroban. Copyright (c) 2007 John Wiley & Sons, Ltd.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
1D/2D NMR; 13C; 1H; Diastereomeric ratio; Inhibitor; NMR; Thrombin
Elenco autori:
Autori di Ateneo:
Link alla scheda completa:
https://air.unimi.it/handle/2434/34797

Aree Di Ricerca

Settori


Settore BIO/10 - Biochimica