Data di Pubblicazione:
2008
Citazione:
Oxidative state and lipid composition of plasma from overweight and moderately obese women / R. Cazzola, M. Rondanelli, R. Trotti, C. Camerotto, B. Cestaro. - In: MEDITERRANEAN JOURNAL OF NUTRITION AND METABOLISM. - ISSN 1973-798X. - 1:1(2008), pp. 19-24. [10.1007/s12349-008-0003-6]
Abstract:
Objective: To determine the oxidative balance and plasma fatty acid composition of overweight and obese women.
Design: Comparative, descriptive study on 60 overweight or obese (> 25 BMI> 33), normotensive, non-diabetic women and 60 age-matched lean healthy women (BMI< 25).
Measurements: Plasma lipid, hydroperoxide, and antioxidants levels, fatty acid composition and lipoproteins susceptibility to peroxidation.
Results: Compared to the lean control group, the patient group had higher lipoprotein susceptibility to peroxidation and higher peroxide levels. On the contrary, the polyunsaturated fatty acids, in particular the omega-3 species, and the antioxidants were lower in the patient group.
Conclusions: The present study shows that overweight and obese people have oxidative balance impairment. The higher susceptibility to peroxidation of lipoproteins is the probable molecular mechanism that promotes a reduction in high unsaturated (and in particular omega-3) fatty acids, as well as antioxidants in the plasma of the overweight and obese subjects.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
oxidative stress ; overweight ; obesity ; lipid peroxidation ; fatty acids
Elenco autori:
R. Cazzola, M. Rondanelli, R. Trotti, C. Camerotto, B. Cestaro
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