Data di Pubblicazione:
2008
Citazione:
Prevalence of CT-detected cerebral abnormalities in an elderly Swedish population sample / M. Simoni, L. Pantoni, G. Pracucci, B. Palmertz, X. Guo, D. Gustafson, I. Skoog. - In: ACTA NEUROLOGICA SCANDINAVICA. - ISSN 0001-6314. - 118:4(2008 Oct), pp. 260-267. [10.1111/j.1600-0404.2008.01010.x]
Abstract:
Objective - To measure the prevalence of computed tomography (CT)-detected cerebral lesions in a population-based sample of elderly persons living in Göteborg, Sweden. Methods - Cerebral CT-scans were performed in the case of 466 women (mean age 74.3 ± 5.1 years) and 191 70-year-old men. A single rater assessed white matter lesions (WML) using four different scales, lacunar lesions, large infarcts, cortical atrophy, and basal ganglia calcifications. Results - White matter lesions frequency assessed by different scales ranged between 54.5% and 68.5%. Lacunar lesions were detected in 46.7% (30.1% had lacunes >5 mm) and cerebral infarcts in 3.0% of participants. Overall, 72.8% of participants evidenced cerebral vascular abnormalities. Severe cortical atrophy was more common in temporal (6.4%) and frontal (6.7%) lobes, than in parietal (1.7%) and occipital (1.1%) lobes. Basal ganglia calcifications were found in 38.7% of participants. WML, lacunar lesions, large infarcts, and degree of cortical atrophy correlated positively with age. More lacunes, basal ganglia calcifications, and occipital lobe atrophy were associated with male gender. Conclusions - Vascular and other brain lesions are very common on CT-scan in an elderly population, but large vascular lesions are rare. This study provides the first reference for the prevalence of CT-detected abnormalities in an elderly Swedish population.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Atrophy; Basal ganglia calcifications; Computed tomography; Infarcts; Lacunes; Population study; Visual rating; White matter lesions; Aged; Brain Diseases; Cerebral Cortex; Cerebrovascular Circulation; Female; Humans; Male; Prevalence; Sweden; Tomography, X-Ray Computed; Neurology (clinical); Neuroscience (all)
Elenco autori:
M. Simoni, L. Pantoni, G. Pracucci, B. Palmertz, X. Guo, D. Gustafson, I. Skoog
Link alla scheda completa: