Data di Pubblicazione:
2018
Citazione:
Plant Flowering : Imposing DNA Specificity on Histone-Fold Subunits / N.B. Gnesutta, R. Mantovani, F. Fornara. - In: TRENDS IN PLANT SCIENCE. - ISSN 1360-1385. - 23:4(2018 Apr), pp. 293-301.
Abstract:
CONSTANS (CO) is a master regulator of flowering time, although the mechanisms underlying its role as a transcriptional regulator are not well understood. The DNA-binding domain of CO shares homology with that of NUCLEAR FACTOR YA (NF-YA), a subunit of the CCAAT-binding trimer NF-Y. Recent publications indicate that CO and its rice homolog HEADING DATE 1 (Hd1) form heterotrimers with the histone-fold subunits of NF-Y to efficiently bind promoter elements in the florigen genes. Differences in the DNA-binding specificities of NF-Y and NF-CO can be conceptualized based on our knowledge of the 3D structure of the NF-Y/. CCAAT complex. Here we discuss the modes of assembly of NF-Y-like heterotrimers and possible models for their activity as flexible sequence-specific transcriptional regulators.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
CONSTANS; Florigen; Flowering; NF-Y; Photoperiod; Transcriptional regulation; Plant Science
Elenco autori:
N.B. Gnesutta, R. Mantovani, F. Fornara
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