Data di Pubblicazione:
2013
Citazione:
Pure autonomic failure with cold induced sweating / J. Idiaquez, R. Fadic, R. Verdugo, J.F. Idiaquez, V. Iodice, D.A. Low, C..J. Mathias, R. Lombardi, G. LAURIA PINTER. - In: AUTONOMIC NEUROSCIENCE: BASIC & CLINICAL. - ISSN 1566-0702. - 176:1-2(2013 Jun), pp. 98-100.
Abstract:
Pure autonomic failure (PAF) is a progressive autonomic neurodegenerative disorder. Cold induced sweating occurred in syndromes with mutations in CRLF1 and CLCF1 genes and in a case of cervical dissection.A patient with PAF developed sweating induced by cool ambient temperatures. He had severe orthostatic hypotension, abnormal cardiovagal reflexes, and paradoxical sweating in the upper trunk at a room temperature of 18. °C. Skin biopsy showed involvement of somatic epidermal unmyelinated nerve fibers. Quantitative sensory testing showed abnormal thresholds to all thermal modalities. Possible mechanisms include cold induced noradrenaline release in remaining autonomic innervation and a supersensitive sudomotor response.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
autonomic; cold sweating; failure; pure; aged; humans; male; pure autonomic failure; sweating; cold temperature; endocrine and autonomic systems; neurology (clinical); cellular and molecular neuroscience
Elenco autori:
J. Idiaquez, R. Fadic, R. Verdugo, J.F. Idiaquez, V. Iodice, D.A. Low, C..J. Mathias, R. Lombardi, G. LAURIA PINTER
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