Data di Pubblicazione:
2007
Citazione:
Cyclodextrins as cosmetic delivery systems / M. Centini, M. Maggiore, M. Casolaro, M. Andreassi, R. Maffei Facino, C. Anselmi. - In: JOURNAL OF INCLUSION PHENOMENA AND MACROCYCLIC CHEMISTRY. - ISSN 1388-3127. - 57:1-4(2007), pp. 109-112. [10.1007/s10847-006-9212-0]
Abstract:
Aim of this work was the study of ferulic
acid/cyclodextrin (CD) association complexes. Ferulic acid (FA) is a compound well-known as antioxidant and photoprotective agent (approved in Japan as sunscreen).
Notwithstanding this, it is poorly suited for
cosmetic applications because it undergoes functional and organoleptic modifications, when it is exposed to air, UV-light and heat. For this reason we prepared a set of FA/CD complexes with the aim to improve its
physico-chemical stability. The inclusion complexes were characterized by differential scanning calorimetry (DSC), X-ray diffraction (XRD), and nuclear magnetic
resonance (1H-NMR). The FA/alpha-CD complex showed the most promising properties (high association constant, high degree of photostability, slower FA release) as sunscreen delivery system.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
CDs inclusion complexes; Ferulic acid; Photostability; Radical scavenging activity; Release
Elenco autori:
M. Centini, M. Maggiore, M. Casolaro, M. Andreassi, R. Maffei Facino, C. Anselmi
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