Consenso sobre tratamiento farmacológico de la dislipidemia aterogénica con terapia combinada estatina-fenofibrato = Consensus for pharmacologic treatment of atherogenic dyslipidemia with statin-fenofibrate combined therapy
Articolo
Data di Pubblicazione:
2016
Citazione:
Consenso sobre tratamiento farmacológico de la dislipidemia aterogénica con terapia combinada estatina-fenofibrato = Consensus for pharmacologic treatment of atherogenic dyslipidemia with statin-fenofibrate combined therapy / C. Aguiar, E. Alegría, R.C. Bonnadonna, A.L. Catapano, F. Consentido, M. Elisaf, M. Farnier, J. Fierrières, P.P. Filardi, N. Hancu, M. Kayikcioglu, A.M.E. Silva, J. Millán, Z. Reiner, L. Tokgozoglu, P. Valensi, M. Viigimaa, M. Vrablik, A. Zambón, J.L. Zamorano, R. Ferrari, M. Blasco, Á. Brea, Á. Díaz, P.G. Santos, A.H. Mijares, T. Mantilla, J. Pedro Botet, X. Pintó. - In: CLÍNICA E INVESTIGACIÓN EN ARTERIOSCLEROSIS. - ISSN 0214-9168. - 28:2(2016 Mar), pp. 87-93. [10.1016/j.arteri.2015.12.001]
Abstract:
LDLc levels are associated with increase of cardiovascular risk, and statins are currently used for their control. Nevertheless, a despite of LDLc levels at goal, a residual risk is persistent, commonly associated with persistent lipids modifications (high triglycerides and low HDLc). So, it is necessary to evaluate triglycerides and HDL to assessment cardiovascular risk. Clinical data are consistent with efficacy and safety of combination therapy with statin and other lipid lowering drugs, for instance fenofibrate. Patients with hipertriglyceridemia and low HDLc are the group with most potential improve. In that patients with atherogenic dyslipidemia, the target for therapeutic objectives related with non-HDL-cholesterol is a priority, because non-HDL-cholesterol is considered as a more accuracy measure to assessment cardiovascular risk.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
atherogenic dyslipidemia; lipid lowering combination therapy; statine-fenofibrate association; atherosclerosis; cardiovascular diseases; cholesterol, hdl; cholesterol, ldl; consensus; drug therapy, combination; dyslipidemias; fenofibrate; humans; hydroxymethylglutaryl-coa reductase inhibitors; hypolipidemic agents; triglycerides; cardiology and cardiovascular medicine; pharmacology (medical)
Elenco autori:
C. Aguiar, E. Alegría, R.C. Bonnadonna, A.L. Catapano, F. Consentido, M. Elisaf, M. Farnier, J. Fierrières, P.P. Filardi, N. Hancu, M. Kayikcioglu, A.M.E. Silva, J. Millán, Z. Reiner, L. Tokgozoglu, P. Valensi, M. Viigimaa, M. Vrablik, A. Zambón, J.L. Zamorano, R. Ferrari, M. Blasco, Á. Brea, Á. Díaz, P.G. Santos, A.H. Mijares, T. Mantilla, J. Pedro Botet, X. Pintó
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