Data di Pubblicazione:
2012
Citazione:
Shaping development with ESCRTs / T.E. Rusten, T. Vaccari, H. Stenmark. - In: NATURE CELL BIOLOGY. - ISSN 1465-7392. - 14:1(2012), pp. 38-45. [10.1038/ncb2381]
Abstract:
Originally identified for their involvement in endosomal sorting and multivesicular endosome (MVE) biogenesis, components of the endosomal sorting complex required for transport (ESCRT) are now known to control additional cellular functions such as receptor signalling, cytokinesis, autophagy, polarity, migration, miRNA activity and mRNA transport. The diverse cell biological functions of ESCRT proteins are translated into a pleiotropic set of developmental trajectories that reflect the wide repertoire of these evolutionarily conserved proteins.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Animals; Endosomal Sorting Complexes Required for Transport; Humans; Multivesicular Bodies; Protein Transport; Cell Biology
Elenco autori:
T.E. Rusten, T. Vaccari, H. Stenmark
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