Comparison between K-nearest-neighbor approaches for conditional entropy estimation: application to the assessment of the cardiac control in amyotrophic lateral sclerosis patients
Contributo in Atti di convegno
Data di Pubblicazione:
2016
Citazione:
Comparison between K-nearest-neighbor approaches for conditional entropy estimation: application to the assessment of the cardiac control in amyotrophic lateral sclerosis patients / A. Porta, B. De Maria, V. Bari, A. Marchi, K. Marinou, R. Sideri, G. Mora, L. Dalla Vecchia (PROCEEDINGS OF THE ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY). - In: Engineering in Medicine and Biology Society (EMBC), 2016 IEEE 38th Annual International Conference of the[s.l] : IEEE, 2016. - ISBN 9781457702204. - pp. 2933-2936 (( Intervento presentato al 38. convegno Annual International Conference of the IEEE EMBS tenutosi a Orlando nel 2016 [10.1109/EMBC.2016.7591344].
Abstract:
The study evaluates the k-nearest-neighbor (KNN) strategy for the assessment of complexity of the cardiac neural control from spontaneous fluctuations of heart period (HP). Two different procedures were assessed: i) the KNN estimation of the conditional entropy (CE) proposed by Porta et al; ii) the KNN estimation of mutual information proposed by Kozachenko-Leonenko, refined by Kraskov-Stögbauer-Grassberger and here adapted for the CE estimation. The two procedures were compared over HP variability recordings obtained at rest in supine position and during head-up tilt (HUT) in amyotrophic lateral sclerosis patients and healthy subjects. We found that the indexes derived from the two procedures were significantly correlated and both methods were able to detect the effect of HUT on HP complexity within the same group and distinguish the two populations within the same experimental condition. We recommend the use of the KNN strategy to quantify the dynamical complexity of cardiac neural control in addition to more traditional approaches.
Tipologia IRIS:
03 - Contributo in volume
Elenco autori:
A. Porta, B. De Maria, V. Bari, A. Marchi, K. Marinou, R. Sideri, G. Mora, L. Dalla Vecchia
Link alla scheda completa:
Titolo del libro:
Engineering in Medicine and Biology Society (EMBC), 2016 IEEE 38th Annual International Conference of the