Hematologic malignancies in pregnancy : Management guidelines from an international consensus meeting
Articolo
Data di Pubblicazione:
2016
Citazione:
Hematologic malignancies in pregnancy : Management guidelines from an international consensus meeting / M. Lishner, I. Avivi, J.F. Apperley, D. Dierickx, A.M. Evens, M. Fumagalli, I. Nulman, F.S. Oduncu, F.A. Peccatori, S. Robinson, K. Van Calsteren, T. Vandenbroucke, F. Van Den Heuvel, F. Amant. - In: JOURNAL OF CLINICAL ONCOLOGY. - ISSN 0732-183X. - 34:5(2016 Feb 10), pp. 501-508. [10.1200/JCO.2015.62.4445]
Abstract:
Purpose: The incidence of hematologic malignancies during pregnancy is 0.02%. However, this figure is increasing, as women delay conception until a later age. Systemic symptoms attributed to the development of a hematologic cancermay overlapwith physiologic changes of pregnancy. A favorable prognosis is contingent upon early diagnosis and treatment. Therefore, a high index of suspicion is required by health care providers. Although timely, accurate diagnosis followed by appropriate staging is essential and should not be delayed due to pregnancy, management guidelines are lacking due to insufficient evidence-based research. Consequently, treatment is delayed, posing significant risks to maternal and fetal health, and potential pregnancy termination. This report provides guidelines for clinical management of hematologic cancers during the perinatal period, which were developed by a multidisciplinary team including an experienced hematologist/oncologist, a high-risk obstetrics specialist, a neonatologist, and experienced nurses, social workers, and psychologists. Methods: These guidelines were developed by experts in the field during the first International Consensus Meeting of PrenatalHematologicMalignancies, which took place in Leuven, Belgium, onMay 23, 2014. Results and Conclusion: This consensus summary equips health care professionals with novel diagnostic and treatment methodologies that aimfor optimal treatment of themother, while protecting fetal and pediatric health.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
consensus; disease management; female; hematologic neoplasms; humans; international agencies; practice guidelines as topic; pregnancy; pregnancy complications, neoplastic; prognosis; medicine (all); oncology; cancer research
Elenco autori:
M. Lishner, I. Avivi, J.F. Apperley, D. Dierickx, A.M. Evens, M. Fumagalli, I. Nulman, F.S. Oduncu, F.A. Peccatori, S. Robinson, K. Van Calsteren, T. Vandenbroucke, F. Van Den Heuvel, F. Amant
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