Data di Pubblicazione:
2015
Citazione:
Modulating Speed-Accuracy Strategies in Major Depression / A. Vallesi, F. Canalaz, M. Balestrieri, P. Brambilla. - In: JOURNAL OF PSYCHIATRIC RESEARCH. - ISSN 0022-3956. - 60(2015 Jan), pp. 103-108. [10.1016/j.jpsychires.2014.09.017]
Abstract:
BACKGROUND:
Depression is associated with deficits in cognitive flexibility. The role of general slowing in modulating more specific cognitive deficits is however unclear.
AIM:
We assessed how depression affects the capacity to strategically adapt behavior between harsh and prudent response modalities and how general and specific processes may contribute to performance deficits.
METHODS:
Patients suffering from major depression and age- and education-matched healthy controls were asked to randomly stress either speed or accuracy during perceptual decision-making.
RESULTS:
Diffusion models showed that patients with depression kept using a less conservative strategy after a trial with speed vs. accuracy instructions. Additionally, the depression group showed a slower rate of evidence accumulation as indicated by a generally lower drift rate.
CONCLUSIONS:
These data demonstrate that less efficient strategic regulation of behavior in depression is due not only to general slowing, but also to more specific deficits, such as a rigid dependence on past contextual instructions. Future studies should investigate the neuro-anatomical basis of this deficit.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Depression; Diffusion models; Executive functions; Flexibility; Perceptual decision-making; Speed-accuracy trade off
Elenco autori:
A. Vallesi, F. Canalaz, M. Balestrieri, P. Brambilla
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