Ctr-1 Mets7 motif inspiring new peptide ligands for Cu(i)-catalyzed asymmetric Henry reactions under green conditions
Articolo
Data di Pubblicazione:
2016
Citazione:
Ctr-1 Mets7 motif inspiring new peptide ligands for Cu(i)-catalyzed asymmetric Henry reactions under green conditions / S. Pellegrino, G. Facchetti, A. Contini, M.L. Gelmi, E. Erba, R. Gandolfi, I. Rimoldi. - In: RSC ADVANCES. - ISSN 2046-2069. - 6:75(2016 Jul 22), pp. 71529-71533. [10.1039/c6ra16255j]
Abstract:
Taking inspiration from the Ctr-1 Mets7 Cu(i) binding motif, effective hybrid catalysts have been developed for asymmetric Henry condensations under green conditions. The introduction of an unnatural dipeptide mimic allowed to increase the catalytic performance. Metal transporters' binding domains could be exploited as a strategy for designing hybrid catalysts for homogeneous catalysis.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Biotin-streptavidin technology; copper transport proteins; Alpha-amino-acids; artificial metalloenzymes; metallopeptide catalysts; secondary structure; CU-II; design; complexes; chemistry
Elenco autori:
S. Pellegrino, G. Facchetti, A. Contini, M.L. Gelmi, E. Erba, R. Gandolfi, I. Rimoldi
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