Burden of pediatrics hospitalizations associated with Rotavirus gastroenteritis in Lombardy (Northern Italy) before immunization program
Articolo
Data di Pubblicazione:
2015
Citazione:
Burden of pediatrics hospitalizations associated with Rotavirus gastroenteritis in Lombardy (Northern Italy) before immunization program / L. Pellegrinelli, L. Bubba, V. Primache, I. Chiaramonte, F.M. Ruggeri, L. Fiore, S. Binda. - In: ANNALI DELL'ISTITUTO SUPERIORE DI SANITÀ. - ISSN 0021-2571. - 51:4(2015), pp. 346-351. [10.4415/ANN_15_04_16]
Abstract:
Aim. Rotavirus is recognized as the main cause of acute gastroenteritis in children under
5 years old, representing a considerable public health problem with a great impact on
social and public health costs in developed countries. This study aims to assess the frequency
and the epidemiological aspect of the hospitalization associated with Rotavirusgastroenteritis
in Lombardy, Northern Italy, from 2005 to 2011.
Methods. The Lombardy Hospital Discharge Database was inquired from the official
data of the Italian Ministry of Health and investigated for acute gastroenteritis (ICD9-
CM code for bacteria, parasitic, viral and undetermined etiologic diarrhea) in primary
and secondary diagnosis in children ≤ 5 years, between 2005 and 2011.
Results. Out of the 32 944 acute-gastroenteritis hospitalizations reported in Lombardy,
the 50.8% was caused by Rotavirus infection; of these, the 65.5% were reported in primary
diagnosis. The peak of Rotavirus-gastroenteritis hospitalization was observed in
February-March in children < 2 years old, with a cumulative prevalence of 64.5%. Patients
admitted to hospital with diarrhea of undetermined etiology (about 14% of overall
acute-gastroenteritis) showed epidemiological characteristics similar to the Rotavirusgastroenteritis,
suggesting that the virus infection could also be involved in at least some
of these.
Conclusion. Our data confirm that Rotavirus are the most important agents involving
in acute gastroenteritis hospitalizations. The use of Hospital Discharge Database had
proved to be a simple tool to estimate the burden and to describe the epidemiological
characteristics of Rotavirus gastroenteritis and could be used as a surveillance activity before
and after the introduction of mass vaccination at national and regional level in Italy.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
acute gastroenteritis; Rotavirus hospitalization; CD9-CM; Rotavirus vaccination; public health
Elenco autori:
L. Pellegrinelli, L. Bubba, V. Primache, I. Chiaramonte, F.M. Ruggeri, L. Fiore, S. Binda
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